Suspensions of paramagnetic colloids are driven to phase separate and self-assemble by a toggled magnetic field. Initially, all suspensions form network structures that span the sample cell. When the magnetic field is toggled, this network structure coarsens diffusively for a time that scales exponentially with frequency. Beyond this break through time, suspensions cease diffusive coarsening an...

BACKGROUND Celecoxib is a selective cyclo-oxygenase 2 inhibitor that relieves pain without affecting platelet function, causing gastrointestinal toxic effects, or increasing the risk of bleeding. OBJECTIVES To develop a suspension formulation for oral celecoxib and to determine its physical and chemical stability when packaged in amber polyvinyl chloride (PVC) bottles and stored with refriger...

Some general physical models are described for the diffusional transport of drugs across membranes of cells in culture suspensions. The models provide a basis for the design and analysis of experiments that are aimed to describe (a) the nature of the principal transport barrier, (b) the kinds of drug species being transported, (c) whether, where and how much solute binding occurs, and (d) the i...

Suspensions are one of the most important dosage forms under liquid orals. A large number of drugs are formulated as suspensions considering their therapeutic and commercial benefits. The aim of the present study is to formulate paracetamol suspensions employing Plantago ovata mucilage as a suspending agent and evaluate the sedimentation stability using near infrared transmission measurements. ...

When a small amount (less than 1%) of a second immiscible liquid is added to the continuous phase of a suspension, the rheological properties of the admixture are dramatically altered and can change from a fluid-like to a gel-like state. These so-called capillary suspensions transition to a gel-like state both if the secondary liquid preferentially wets the particles (pendular state) and even i...

BACKGROUND Prescribing of diclofenac for children usually involves a dose different from commercially available strengths. This drug is available only as tablets, which can be divided only so many times before the dose obtained becomes inaccurate. In addition, children may have difficulty swallowing tablets. For these reasons, a compounding formula for a liquid dosage form is essential to ensur...

Dense suspensions of multiarm star polymers are known to develop liquidlike microstructure, which has been attributed to the similarities between high functionality stars and colloidal particles interacting via soft, long ranged potentials. Recent experimental studies reported a counterintuitive solidification of suspensions with f=128 , upon increase of the temperature in marginal solvents. We...