1. Rates of oxygen consumption of albino and hairless mice were measured in a metabolism chamber during periods of approximately 5 or 24 hr. Rectal temperature was measured before and after each period. The chamber temperatures used were 22, 30 and 32 degrees C for both albino and hairless, and in addition 34 and 36 degrees C for the hairless mice.2. The mean age and body weight of the albino m...

The nude mouse does not reject xenografts of malignant and nonmalignant tissues of mammalian or avian origin, due to a deficiency of functional T-lymphocytes. In this study, tissue from a cold-blooded vertebrate, a teleost fish, was for the first time successfully transplanted to Swiss albino nu/nu mice. Malignant melanotic melanoma of Xiphophorus transplanted to nude mice showed progressive gr...

With a view to examine the effects of defined doses of retinyl palmitate (Vit. A) on limb morphogenesis and their effects at the critical time in mouse embryos, pregnant Swiss Webster albino mice were administered retinyl palmitate (10000 or 15000 IU/kg, i.p.) on different days of pregnancy. Vitamin A in 15000 IU/kg, i.p. dose was most effective as produced malformations in the forelimbs by day...

Radioprotective effectiveness of a combination of HT and AET was evaluated by radiation induced micronucleus screening in mouse bone marrow. Swiss albino mice were injected with 2-Aminoethylisothiouronium bromide hydrobromide (AET)+5-hydroxy-L-tryptophan (HT) 30 minutes prior to a single whole body exposure of 8 and 12 Gy Co60 gamma rays. Animals were sacrificed at different intervals viz., 24 ...

zona pellucida contains receptors for a variety of plant lectins, glycoproteins that bind to specific saccharide determinants (Oikawa, Yanagimachi & Nicol¬ son, 1973; Oikawa, Nicolson & Yanagimachi, 1974; Nicolson, Yanagimachi & Yanagimachi, 1975). Some of these lectins can bind to the zona pellucida and induce egg agglutination and/or cause changes in the ability of the exterior region of the ...

Protein nutritional status indicators were studied in weanling albino Swiss mice infected with S. mansoni and fed the Regional Basic Diet (RBD) from Northeast Brazil, a multideficient diet of low-protein content. Each mouse was infected percutaneously with 80 cercariae. The experiment lasted 63 days. The growth curve, food consumption, protein intake, weight gain, Protein Efficiency Ratio (PER)...

LIGHTNER, LAWRENCE K., AND ULXJER, MAHLIN J. 1974. Trickinellu spiralis: Effect of environmental temperature on mice. Experimental Pamsitology 35, 262-265. Effects of environmental temperature on Trichinellu spiral&infected mice were studied. Groups of mice were acclimated to temperatures of 8-10 C, 20-25 C, and 36 C for a period of 5 clays and then were exposed to 100 infective juveniles of T....

Sterile thermoreversibly gelling systems based on chitosan- glycerol phosphate were developed for intraperitoneal delivery of the antineoplastic agent 5-FU. The formulation was evaluated for gelling characteristics and in vitro drug release. Drug free gels were evaluated for in vitro cytotoxicity in L-929 mouse fibroblast cells. Drug loaded gels were subjected to acute toxicity studies in Swiss...

Adult Swiss albino male mice exposed to mercuric chloride via drinking water at 5 μg/ml for 100 days revealed significant reduction in the wet weight and severe histopathological changes in male accessory organs, poor level of serum testosterone and infertility. These effects were reduced remarkable and fertility was restored when drug (12.50 mg/mouse/day orally) was administered during mercury...

background: glycowithanolides (withaferin a), is one of the main withanolides active principle isolated from plant withania somnifera and is claimed that it possess the aphrodisiac, sedative, rejuvenate and life prolonging properties. objective: in the present investigation, antioxidant activity of active principles of withania somnifera was tested against d-galactose induced oxidative stress i...