Subjective symptom assessment should be a fundamental component of health-related quality of life (HRQL) assessment in end-stage renal disease (ESRD). Unfortunately, no symptom checklist has established reliability or validity in ESRD. We report the validation of a modified Edmonton Symptom Assessment System (ESAS) in 507 dialysis patients who concurrently completed the Kidney Dialysis Quality ...

PURPOSE Stereotactic body radiation therapy (SBRT) is increasingly utilized as primary treatment for clinically localized prostate cancer. While acute post-SBRT urinary symptoms are well recognized, the late genitourinary toxicity of SBRT has not been fully described. Here, we characterize the clinical features of late urinary symptom flare and recommend conservative symptom management approach...

There are no validated criteria to measure skin response in chronic GVHD. In a prospectively assembled, multicenter cohort of patients with chronic GVHD (N = 458), we looked for correlation of change in several different scales recommended by the National Institutes of Health (NIH) Consensus with clinician and patient perception of change and overall survival. Of the clinician scales, the NIH c...

BACKGROUND & OBJECTIVES Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with tr...

We assessed the relationship of American Urological Association (AUA) urinary symptom score and tumor stage in men treated for localized prostate cancer. Methods: Participants in our study were found through urology and radiation oncology clinics, and all eligible patients were asked to take part. All patients had been initially diagnosed on the basis of rising PSA or abnormal physical examinat...

background although heller myotomy is one of the most effective treatments for achalasia, it may be associated with early or late symptom relapse in some patients. therefore, additional treatment is required to achieve better control of symptoms. aim : to evaluate the safety and efficacy of pneumatic balloon dilation (pbd) in patients with symptom relapse after heller myotomy. methods thirty si...

METHODS. The subjects (85% polysensitized, 25% with asthma) were randomized 1:1 to receive once-daily MK7243 (2800 BAU P pratense) or placebo. The first dose was given at the investigator’s office; subsequent doses were self-administered at home. The primary end point was total combined score (TCS) (composed of rhinoconjunctivitis daily symptom score plus daily medication score) over the entire...

BACKGROUND Although chronic rhinosinusitis (CRS) is increasing in prevalence and incidence, its diagnosis and treatment still pose a challenge. The Task Force on rhinosinusitis (TFR) advocates the use of symptom based criteria. However, many otorhinolaryngologists depend on diagnostic nasal endoscopy and computed tomography (CT) of paranasal sinuses for diagnosis of CRS. Computed tomography has...

OBJECTIVE Impaired quality of life and psychological distress are common in irritable bowel syndrome (IBS) and may be associated with unhelpful cognitions. Hypnotherapy (HT) is effective in improving both symptoms and quality of life in patients with IBS, and this study was designed to determine whether this improvement is reflected in cognitive change using a validated scale recently developed...