PATIENT Female, 14 FINAL DIAGNOSIS: Multiple pituitary hormone deficiency Symptoms: Hyponatremia Medication: - Clinical Procedure: Endovascular embolectomy Specialty: Endocrinology and Metabolic Objective: PATIENT complains/malpractice. BACKGROUND Hyponatremia is one of the most common electrolyte disorders. Depending on the patient's hydration status, hyponatremia can be classified as hypovo...

Guillain Barre syndrome (GBS) is a rare but potentially fatal immune mediated disorder of peripheral nerves and nerve roots usually triggered by infections characterized ascending paralysis with or without sensory symptoms, hyporeflexia to areflexia. Usually preceded gastrointestinal respiratory infection. Post COVID-19 neurological manifestation include GBS, transverse myelitis etc., occur at ...

Syndrome of inappropriate secretion of antidiuretic hormone (SIADH), hypothalamic hypogonadism and alopecia universalis occurred in a 31-year-old female with insulin-dependent diabetes mellitus (IDDM). Despite various clinical investigations and careful observation for 20 months, the cause and pathogenesis of SIADH and hypothalamic hypogonadism were not elucidated. The complex of these disorder...

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) can be caused by a variety of drugs. Dopaminergic drugs might enhance the secretion of the antidiuretic hormone arginine vasopressin by reducing γ-amino butyric acid release through the dopaminergic receptor in supraoptic nucleus. A 75-year-old woman with Parkinson's disease developed asthenia, delirium, aggravated parkinsonia...

BACKGROUND Cerebral salt wasting syndrome (CSWS), syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diabetes insipidus (DI) are frequently found in postoperative neurosurgery. PURPOSE To identify these syndromes following neurosurgery. METHOD The study included 30 patients who had been submitted to tumor resection and cerebral aneurysm clipping. Sodium levels in serum and...

はじめに SIADH(syndrome of inappropriate secretion of ADH)は 低ナ トリウム麺症を主徴とする病態 である.これを非SIADHの 低ナ トリウム血症と比 較した場合,SIADHで は水分摂取の制限が低ナ ト リウム血症 の治療上有 効であ るの に対 と,非 SIADHで は血清ナ トリウム値の正常化 に先だつ て,脱 水や虚脱等,液 きに危険を伴 う副作用を招 く点で,両 者の鑑別診断は臨床上大き な意味をも つものといえる. ,ラ ジナイム ノアッセイによる血中ADHの 測定が可能 となつて,各 種の低ナ トリウム血症に ついて血中ADH濃 度を検討すると, SIADHの み ならず非SIADHにお いて も多 くの症例 で血 中 ADH濃 度の上昇がみ とめられる.非SIADHの 低 ナ トリウム血症の発症や維持に際 とて も,血...

Accessible online at: www.karger.com/journals/nef Venlafaxine, a 2-phenyl-2 (1-hydroxycycloalkyl) ethylamine derivate, is an inhibitor of both serotonin and norepinephrine re-uptake and was termed a ‘dual uptake inhibitor’ [1]. We report on a venlafaxine-treated patient who developed Fanconi’s syndrome (FS) and hyponatremia secondary to inappropriate antidiuretic hormone secretion syndrome (SIA...

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia in cancer patients. It is most frequently reported in association with small-cell lung cancer, but has been reported in other cancers as well. Here we report the case of a patient with myelodysplastic syndrome and blast crisis who developed concurrent hyponatremia. The patient failed to respond to...

We describe the first reported case of a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) induced by low-dose tacrolimus in a patient with autoimmune disease. A 41-year-old man with systemic lupus erythematosus (SLE) developed hyponatremia induced by SIADH after administration of tacrolimus (0.06 mg/kg per day). In this case, the hyponatremia promptly resolved upon withdrawal...

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia, and many medications have been associated with SIADH. Pregabalin is a drug used for the treatment of neuropathic pain, though common adverse effects include central nervous system disturbance, peripheral edema, and weight gain. However, hyponatremia caused by pregabalin has b...