Purpose: The aim of this study is to observe the synergistic effect of two active compounds of secang, brazilin and brazilein, combined with cisplatin on WiDr colon cancer cells. Methods: Cytotoxic activities of brazilin (Bi) and brazilein (Be) in single and in combination with cisplatin (Cisp) were examined by MTT assay. Synergistic effect was analyzed by combination index (CI) parameter. Apop...

Objective: In view of the national key project for infectious diseases “ the retreatment research of tuberculosis”, we determined the in vitro anti-mycobacterial activity of four drugs in the treatment, pasiniazid (Pa), moxifloxacin (Mfx), Rifabutin (Rfb) and rifapentini (Rft) in combination to multidrug-resistant and extensively drug-resistant mycobacterium tuberculosis. Method: Three-dimensio...

Selaginella tamariscina is a traditional herb used in medicine. Phytochemical amentoflavone, a biflavonoid class of flavonoids, was isolated from the plant of Selaginella tamariscina. In this study, the antibacterial effects and combination effects of amentoflavone and conventional antibiotics such as ampicillin, cefotaxime, and chloramphenicol were investigated. These results showed that ament...