Toxoplasma gondii infection was diagnosed in a full term stillborn reindeer (Rangifer tarandus) fetus. The fetus had encephalitis and placentitis associated with T. gondii. Tissue cysts were identified histologically in sections of brain and tachyzoites were present in placenta and the myocardium. Protozoa in the brain, heart, and placenta stained positively with T. gondii antibodies, but not w...

By using stage-specific monoclonal antibodies, an in vitro model has been developed to analyze the kinetics of expression of stage-specific antigens during the conversion process between tachyzoites and bradyzoites of Toxoplasma gondii. Following infection of murine macrophages with bradyzoites, the expression of bradyzoite-specific antigens declined, whereas the expression of tachyzoite-specif...

Toxoplasma gondii Using cutting-edge cryo-cellular tomography technology, detailed molecular anatomy of gondii, particularly during the budding endodyogeny stage tachyzoites, is shown in article number 2206595 for first time. Based on these, Qiang Guo and co-workers propose that conoid fiber, a vital component conoid, may have microtubule origins.

BACKGROUND Toxoplasmosis is a public health problem worldwide. This complication principally affects immunodeficient patients and pregnant women. Toxoplasma gondii is an opportunistic parasite, causing severe illness among and death of high-risk individuals and treatment is becoming increasingly difficult owing to side effects and low efficacies of drugs. OBJECTIVES In this study, we investig...

Toxoplasma gondii is a protozoan parasite with a broad range of intermediate hosts. Chickens as important food-producing animals can also serve as intermediate hosts. To date, experimental studies on the pathogenicity of T. gondii in broiler chickens were rarely reported. The objective of the present study was to compare the pathogenicity of 5 different T. gondii strains (RH, CN, JS, CAT2, and ...

background: this study was undertaken to evaluate the viability, infectivity and immunity of toxoplasma gondii tachyzoites exposed to 2-(naphthalene-2-ylthio)-1h-indole.   methods : tachyzoites of rh strain were incubated in various concentrations of 2- (naphthalene-2-ylthio)-1h-indole (25-800μm) for 1.5 hours. then, they were stained by pi and analyzed by fluorescence-activated cell sorting (f...

Neospora caninum (N. caninum) is an apicomplexan parasite and causes abortion and congenital neosporosis in cattle worldwide. In this study, we evaluate the virulence of a N. caninum isolate on mouse strain C57BL/6. Six groups of five mice C57BL/6 were intraperitoneally inoculated with 1 × l07, 1.5 × l07, 2 × l07, 3 × l07 and 4 × l07 tachyzoites and a control inoculum of DMEM, respectively. Cli...

background: toxoplasmosis is considered as one of the most common infectious diseases caused by the protozoan parasite toxoplasma gondii . tachyzoite is the main form of toxoplasma and continuously is maintained in cell culture or injected into the mice peritoneal cavity. this study was designed to evaluate the survival rate of rh strain of t. gondii tachyzoites in different cell free, nutrient...