Aim Although stroke is among the leading causes of death and long-term disability, there are few effective treatments for limiting the severity of neurological sequelae. We evaluated the effects of 29 medicinal herbs listed in the Pung chapter of the 17th century Korean medical text Dongui Bogam on stroke symptoms in a mouse model of cerebral ischemia. Methods Focal cerebral ischemia was indu...

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the selective loss of motor neurons. There is no effective treatment or drug against ALS, and the precise mechanisms leading to the selective loss of motor neurons are still unknown. We investigated the effect of a Chinese prescription, Wen-Pi-Tang, on the ALS model mouse SOD1(G93A). Although the or...

INTRODUCTION Qing fei tang, which is used for various respiratory diseases, is useful for reducing relapse of aspiration pneumonia and bronchopneumonia in stroke, but the effect remains unknown in Parkinson's syndrome. We report two cases of Japanese patients with progressive supranuclear palsy and relapsing aspiration pneumonia and bronchopneumonia, which was successfully prevented by qing fei...

An accurate and reliable method of high-performance liquid chromatographic fingerprint combining with multi-ingredient determination was developed and validated to evaluate the influence of sulfur-fumigated Paeoniae Radix Alba on the quality and chemical constituents of Si Wu Tang. Multivariate data analysis including hierarchical cluster analysis and principal component analysis, which integra...

Dianous zhujianqingi Tang & Li, 2011 syn. n. is synonymised with Dianous cyaneovirens (Cameron, 1930). Additional records of Dianous yao Rougemont, 1981, Dianous haraldi Puthz, 2000 and Dianous huanghaoi Tang & Li, 2011 are provided.

We give a combinatorial interpretation of a certain positivity conjecture of Chern-SchwartzMacPherson classes, as stated by P. Aluffi and the author in a previous paper. It translates into a positivity property for a sum of p × p determinants consisting of binomial coefficients, generalizing the classical Theorem of Lindström-Gessel-Viennot et al. which computes these determinants in terms of n...

We present two results characterizing minimizers of the Chan-Esedoḡlu LTV functional F (u) ≡ ∫ |∇u|dx + λ ∫ |u − f |dx; u, f : R → R. If we restrict to u = χΣ and f = χΩ, Σ,Ω ∈ R, the LTV functional reduces to E(Σ) = Per(Σ) + λ|Σ M Ω|. We show that there is a minimizer Σ such that its boundary ∂Σ lies between the union of all balls of radius nλ contained in Ω and the corresponding union of n λ ...

Gugijihwang-Tang (the herbal formula PM012), a decoction consisting of several herbs including Rehmanniae Radix Preparata, has been widely used as herbal treatment for dementia. In order to investigate the neuroprotective action of this prescription, we examined the effect of Gugijihwang-Tang on learning and memory using the Morris water maze and [F-18]FDG micro PET neuroimaging technique. Afte...