Background: The incidence of tuberculosis (TB) has increased in recent years in both developed and developing countries. Skeletal tuberculosis occurs in approximately 1% of patients with tuberculosis. The present study aimed to evaluate the epidemiology of skeletal tuberculosis in Golestan province in northeastern Iran during 2005-2014.Methods: In the present retrospective study, the epidemiolo...

the present study aimed to explore some risk factors affected the mean of the number of tuberculosis (tb) in west azerbaijan province, iran between 2001 and 2010.our time series study analyzed the data of 2,560 tb patients as registered with tb patients care system in west azerbaijan province from early 2001 to 2010. a checklist was prepared for collecting the data and they were then analyzed i...

Background: Tuberculosis (TB) is one of the most significant health-care problems worldwide. The host’s genetics play an important role in the development of TB in humans. The disease progresses through several stages, each of which can be under the control of different genes. The precise genes influencing the different stages of the disease are not yet identified. The aim of the current study ...

conclusions although very rare, mdr miliary tb can be seen in immunocompetent subjects. we, thereby, emphasize that early recognition and initiation of treatment are associated with a significant improvement in outcomes. tuberculosis remains a serious worldwide health problem associated with high morbidity and mortality. case presentation our case was a young female patient with in vitro fertil...

  Introduction: Development of effective immunodiagnostic methods for detection of Mycobacterium tuberculosis infection is crucial. Serodiagnostic methods, based on antibody response to specific antigens could provide promising approaches for rapid, economical and easy to perform diagnostic tests which are crucial for tuberculosis (TB) control. In this study, the level of IgG antibody responses...

Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: Ninety...

background: on tuberculosis control standpoint, the treatment of children with tb is not considered a priority as they rarely transmit the disease and contribute little to the maintenance of the tuberculosis epidemic. therefor this study conducted to describe pediatric tb cases, and to identify pattern of risk factors in non-endemic communities materials and methods: the present cross- sectiona...

background: tuberculosis (tb) is currently one of the greatest problems in public health. mycobacterium tuberculosis infects about one third of the world's population, of whom more than 80% are living in developing countries. the incidence and prevalence of tb are very different in various parts of iran and also throughout the world. golestan province is one of the areas in the country where th...

this systematic review intended to combine factors associated with tuberculosis treatment non-adherence and lost to follow up among tb patients with/without hiv in developing countries. comprehensive remote electronic databases (medline, (pmc, pub med central), google scholar and web of science) search was conducted using the following keywords: tuberculosis, treatment, compliance, adherence, d...