نتایج جستجو برای: tc 99m psma

تعداد نتایج: 32922  

Journal: :Genetics and molecular research : GMR 2009
S J Hosseinimehr A Ahmadi D Beiki A Mahmoudzadeh M Babaei E Habibi

The radiotracer technetium-99m methoxyisobutyl isonitrile ((99m)Tc-MIBI) has been widely used for myocardial blood flow imaging. We investigated the genotoxicity of (99m)Tc-MIBI in cultured human lymphocytes at the same concentration used in patients. Radioactivity doses were determined in whole blood at 5 min post-injection of 20 mCi (99m)Tc-MIBI in patients. Subsequently, whole blood of human...

Journal: :Metal-Based Drugs 2000
Luigi G. Marzilli Lory Hansen Andrew Taylor Rene Lachicotte

We report here a chemical study on a Re analogue of one of the few cationic Tc-99m tracers previously investigated as an agent for effective renal plasma flow (ERPF) measurement. Cationic Tc-99m tracers have the potential for overcoming problems associated with common anionic Tc-99m tracers in patients who have developed a uremic state. The Tc-99m-DACH tracer, prepared from 1,2-diaminocyclohexa...

2015
Eun-Mi Kim Seok Tae Lim Myung-Hee Sohn Hwan-Jeong Jeong

Colloidal particle size is an important characteristic that allows mapping sentinel nodes in lymphoscintigraphy. This investigation aimed to introduce different ways of making a (99m)Tc-tin colloid with a size of tens of nanometers. All agents, tin fluoride, sodium fluoride, poloxamer-188, and polyvinylpyrrolidone (PVP), were mixed and labeled with (99m)Tc. Either phosphate or sodium bicarbonat...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003
Martin Charron

UNLABELLED To evaluate whether scintigraphy with (99m)Tc-labeled white blood cells (WBC) can assess the intensity of bowel inflammation, a large dataset of laboratory values and clinical activity indices was correlated with (99m)Tc-WBC scintigraphy in children with Crohn's disease (CD), ulcerative colitis (UC), and miscellaneous colitis (MC). Also evaluated was whether stratification of childre...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008
Sibyll Goetze William C Lavely Harvey A Ziessman Richard L Wahl

UNLABELLED Brown adipose tissue (BAT) is retained into adulthood in some patients. It has been imaged using several radiopharmaceuticals, including (18)F-FDG. Using SPECT/CT, we assessed whether and how frequently uptake of (99m)Tc-methoxyisobutylisonitrile ((99m)Tc-MIBI) was present in expected locations of BAT. METHODS A total of 205 SPECT/CT scans using (99m)Tc-MIBI for parathyroid imaging...

Journal: :Sarcoma 2001
Georgios Karanikas Wolfgang Köstler Alexander Becherer Robert Dudczak Michael Krainer Kurt Kletter

Purpose. Tc-99m tetrofosmin launched for myocardial studies has recently also shown a good detectability for several tumors. Data on PNET imaging by Tc-99m tetrofosmin are not yet available.Patient and method. In the case of a 21-year-old man suffering from pelvis PNET, Tc-99m tetrofosmin scintigraphy was performed additionally to CT and MRI.Results. The gluteal and iliac tumor masses were visu...

Journal: :Molecules 2013
Chunxiong Lu Quanfu Jiang Minjin Hu Cheng Tan Yu Ji Huixin Yu Zichun Hua

A novel annexin A5 derivative (cys-annexin A5) with a single cysteine residue at its C-terminal has been developed and successfully labeled in high labeling yield with (99m)Tc by a ligand exchange reaction. Like the 1st generation (99m)Tc-HYNIC-annexin A5, the novel (99m)Tc-cys-annexin A5 derivative shows in normal mice mainly renal and, to a lesser extent, hepatobiliary excretion. In rat model...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013
Julien Dimastromatteo Alexis Broisat Pascale Perret Mitra Ahmadi Didier Boturyn Pascal Dumy Daniel Fagret Laurent M Riou Catherine Ghezzi

UNLABELLED Vascular cell adhesion molecule 1 (VCAM-1) plays a major role in the chronic inflammatory processes involved in vulnerable atherosclerotic plaque development. We previously showed that the (99m)Tc-labeled major histocompatibility complex 1-derived peptide B2702p bound specifically to VCAM-1 and allowed the ex vivo imaging of atherosclerotic lesions in Watanabe heritable hyperlipidemi...

Journal: :Cancer 2011
Xiao Shen Wang Ying Jian Zhang Xiao Lan Liu Zheng Rong Zhou Chao Su Hu Avraham Eisbruch

BACKGROUND The authors prospectively evaluated the correlation between technetium-99m methoxyisobutyl isonitrile ((99m) Tc-MIBI) accumulation in tumors and response to induction chemotherapy in patients with nasopharyngeal carcinoma (NPC). METHODS Eighty-six patients with locally advanced NPC underwent single-photon emission computed tomography 15 minutes after an intravenous injection of 740...

2013
Qian Zhao Ping Yan Rong Fu Wang Chun Li Zhang Ling Li Lei Yin

INTRODUCTION Visualization of tumor angiogenesis using radionuclide targeting provides important diagnostic information. In previous study, we proved that an arginine-arginine-leucine (RRL) peptide should be a tumor endothelial cell specific binding sequence. The overall aim of this study was to evaluate whether (99m)Tc-radiolabeled RRL could be noninvasively used for imaging of malignant tumor...

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