GTPases of the Rho family control a wide variety of cellular processes such as cell morphology, motility, proliferation, differentiation, and apoptosis. We report here the characterization of a new Rho member, which shares 85% and 78% amino acid similarity to TC10 and Cdc42, respectively. This GTPase, termed as TC10-like (TCL) is encoded by an unexpectedly large locus, made of five exons spanni...

The generalized quantum master equation provides a powerful tool to describe the dynamics in quantum impurity models driven away from equilibrium. Two complementary approaches, one based on Nakajima-Zwanzig-Mori time-convolution (TC) and the other on the Tokuyama-Mori time-convolutionless (TCL) formulations provide a starting point to describe the time-evolution of the reduced density matrix. A...

BACKGROUND Entrainment criteria for macroreentrant arrhythmias are based on detecting fusion between tachycardia and paced wavefronts, but this is often difficult for atrial tachycardias (AT) after ablation of atrial fibrillation. METHODS AND RESULTS With the use of a multipolar catheter, pacing was performed from electrodes within the coronary sinus showing activation later than adjacent ele...

•PMMR is a compartment based radical hysterectomy in endometrial cancer.•Pelvic PMMR may be combined with ICG guided Targeted Compartmental Lymphadenectomy (TCL).•Video of Pelvic PMMR and TCL technique may be basis for a prospective study.

The past decades have seen a growing trend both in the quantity and quality of translation children’s literature (TCL). There been number publications focusing on TCL. However, few studies investigated TCL from perspective norm theory, prior research has primarily concentrated implied reader while ignoring actual readers. This study aimed to investigate expectancy norms real readers English-Chi...

Shen, ZL; Gordon, JL; Cheng, J; +Li, ZM +Departments of Biomedical Engineering, Orthopaedic Surgery, and Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, OH [email protected] INTRODUCTION: The transverse carpal ligament (TCL) forms the palmar boundary of the carpal tunnel, prevents volar migration of the underlying median nerve and flexor tendons, and plays a critical role in regul...

Thermochemiluminescence (TCL) of organic compounds or biological substances is an interesting phenomenon and has been applied to polymer analysis and medical diagnostics. We improve traditional TCL assays using the assistance of catalytic nanomaterials and construct a nanomaterials array for the discrimination of three subtypes of proteins (albumin from human serum, bovine serum and porcine ser...

This paper describes a new toolkit for X11 called Tk. The overall functions provided by Tk are similar to those of the standard toolkit Xt. However, Tk is implemented using Tcl, a lightweight interpretive command language. This means that Tk’s functions are available not just from C code compiled into the application but also via Tcl commands issued dynamically while the application runs. Tcl c...

Free Cy5.5 dye and Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION) have been routinely used for in vivo optical imaging. However, there is little information about the distribution and accumulation of free Cy5.5 dye and Cy5.5-labeled TCL-SPION in the tissues of mice. Free Cy5.5 dye (0.1 mg/kg body weight) and Cy5.5-labeled TCL-SPION (15 mg/kg body wei...

BACKGROUND Canine T-cell lymphoma (TCL) is clinically and histologically heterogeneous with some forms, such as T-zone lymphoma (TZL), having an indolent course. Immunophenotyping is an important tool in the classification of TCL in people, and can be equally useful in dogs. HYPOTHESIS/OBJECTIVES We hypothesized that loss of expression of the CD45 antigen is a specific diagnostic feature of T...