MicroRNAs (miRNAs) are small RNA molecules that play important roles in gene regulation and translational repression. The mechanisms that facilitate miRNA target binding and recognition have been extensively studied in recent years. However, it is still not well known how the miRNA regulation is affected by the location and the flanking sequences of miRNA target sites. In this study, we systema...

Abstract This paper examines the problem of computing a canonical smallest covering region for an arbitrary discrete probability distribution. optimisation is similar to classical 0–1 knapsack problem, but it involves over set that may be countably infinite, raising computational challenge makes non-trivial. To solve we present theorems giving useful conditions optimising and develop iterative ...

Despite significant progress, the general functional and evolutionary significance of the untranslated regions (UTRs) of eukaryotic transcripts remain mysterious. Particularly mysterious is the common occurrence of spliceosomal introns in transcript UTRs because UTR splicing is not necessary for restoration of transcript coding sequence. In general, it is not known to what extent such splicing ...

Solid waste management has been known to play an important role in public health and the environmental status of developing countries. Waste assessment can help researchers and governors in management programs and devising alternative plans in order to improve public health and economical savings. In the present study, statistical estimations regarding waste generation and type of solid wastes ...

Interest in arid ecosystems as a source of food supply for rapidly increasing population of the world, on the one hand, and the problems pertaining to the climatic characteristics, water shortages and soil sensitivity for the inhabitants in such areas, on the other have prompted efforts at both national and international levels to develop a better understanding of these problems as well as to f...