The serum response factor (SRF) coactivator myocardin-related transcription factor A (MAL/MKL1/MRTF-A), the nuclear transport and activity of which is regulated by monomeric actin, has been implicated in tension-based regulation of SRF-mediated transcriptional activity. However, the mechanisms involved remain unclear. We used fibroblasts grown within collagen matrices to explore whether MRTF-A ...

A powerful and versatile method of shape-preserving interpolation is developed in terms of piecewise exponential functions with a tension factor associated with each interval. Knots coincide with data points, and the interpolant is formulated in terms of its values and first derivatives at these points. For a given set of derivatives, this enables the efficient computation of the minimum tensio...

Psychometric properties of a new scale that measures motivations towards alcohol use were examined using a sample of 412 male alcohol users in Sri Lanka aged 16-30 years. In addition, associations between drinking motives and drinking frequency were explored. Confirmatory factor analysis showed that a 3-factor model consisting of the factors personal enjoyment, tension reduction, and social pre...

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The aim of this research is to design a controlling loop that eliminates the irregularities in yarn tension during the winding process. In order to achieve this, we employed a relative feedback industrial control system. The yarn tension sensor measures the tension. Its output is analyzed in the automatic controlling unit. This unit adjusts the tension level according to feedback signals, thus ...

An elastoplastic phase-field model is used to investigate the deformation mechanisms of yttria stabilized tetragonal zirconia in presence defects. A remarkable tension-compression asymmetry detected. higher strength and a lower degree transformation are observed compression than tension. Also, mechanism asymmetric depending on crystal orientation. For some cases (other cases), phase absent tens...

Two different methods have been used to fatigue test four bone cements. Each method has been used previously, but the results have not been compared. The ISO 527-based method tests a minimum of 10 samples over a single stress range in tension only and uses Weibull analysis to calculate the median number of cycles to failure and the Weibull modulus. The ASTM F2118 test regime uses fewer specimen...

Evidence of the existence of a transient surface tension between two miscible fluid phases is given. This is done by making use of a density matched free of gravity perturbations, binary liquid of isobutyric acid and water, which presents a miscibility gap and is studied by light scattering. The experiment is performed very near the critical point of the binary liquid, where the diffusion of ph...

optimizing the herbicide dose by the addition of adjuvants is an acceptable way to increase performance and to reduce the risk of side effects from herbicides. therefore, to detect a suitable adjuvant for clodinafop-propargyl against little seed canary grass (phalaris minor retz.). greenhouse experiment were conducted as factorial in completely randomized design with four replications for compa...

Since the first true herniorrhaphy was performed by Bassini over 100 years ago, all modifications and surgical techniques have shared a common disadvantage: suture line tension. The anatomic, physiologic, and pathologic characteristics of hernia recurrence are examined. The prime etiologic factor behind most herniorrhaphy failures is the suturing together, under tension, of structures that are ...