Abstract Objective: To assess the incidence of thrombocytopenia and changes in various platelet parameters, in culture positive neonatal sepsis. Methods: This was prospective study conducted over a period of one year from December 2009 to November 2010 in neonatal intensive care unit of DDUH Hospital, a tertiary care hospital in Delhi, North India. All babies who were admitted during this perio...

Accepted 6 November 1995 Abstract Group B ,-haemolytic Streptococcus (GBS) may cause severe septic shock and death in neonates, whereas this is rarely the case in adults. As impaired red blood cell (RBC) deformability might disturb microcirculation in septic shock, the in vitro effects of GBS (1-7X108 cfu/ml) on RBC deformation (rheoscope) and haemolysis were studied in blood from preterm infan...

Conventional coagulation tests might be inadequate to explore mechanisms regulating thrombin generation in neonates, because they do not allow full activation of the reduced levels of protein C. Therefore, they do not reflect the action of pro- and anti-coagulants as does the endogenous thrombin potential assessed in the presence of thrombomodulin. Endogenous thrombin potential measured without...

BACKGROUND Maternal smoking during the third trimester reduces the birthweight of the full-term neonate. We assessed the relationship between the timing of exposure to maternal smoking, gestational period, weight and body length for both full-term and preterm neonates. METHODS A retrospective study with a questionnaire was conducted in 1194 infants who participated in the official medical exa...

AIMS To determine whether it is possible to assess baroreflex sensitivity in neonates by studying only spontaneous variation in systolic blood pressure and heart rate. METHODS ECG and non-invasive blood pressure signals were continuously studied in 14 preterm neonates (term 29-32 weeks) and five term neonates (term 40-41 weeks). Non-invasive blood pressure measures were obtained using a Finap...

Background Because of severe adverse effects of hyperbilirubinemia on newborns central nervous system diagnosis of its risk factors before delivery can prevent these effects.  This study aimed to determine the relationship between types of delivery with jaundice during the first week of life in Term neonates. Materials and Methods In this retrospective study, all term neonates born in Amiralmo...

Background: Dyslipidemia is attributed for coronary artery diseases. Early detection of dyslipidemia in neonatal cord blood could help to identify possible future risk factors diseases new born.
 Aims and Objectives: This study was undertaken compare lipid profile small gestational age (SGA) or preterm appropriate (AGA) near-term neonates.
 Material Methods: A total 60 neonates were i...

OBJECTIVE To assess the utility of 24 and 48 hours transcutaneous bilirubin (TcB) index for predicting subsequent significant hyperbilirubinemia in healthy term neonates. METHODS TcB indices were obtained for healthy, breastfed, term AGA newborns at 24 +/- 2, 48 +/- 2 and subsequently at intervals of 24 hours. Neonates with illness, on treatment and positive Direct Coomb's test were excluded....