[Purpose] Painful diabetic polyneuropathy occurs as a complication in 16% of all patients with diabetes mellitus. [Subjects and Methods] A clinical, prospective open-label randomized intervention study was conducted of 60 adult patients, with distal sensorimotor diabetic neuropathy two groups of 30 patients, with diabetes mellitus type 2 with distal sensorimotor diabetic neuropathy. Patients in...

It has been suggested that the tethering caused by binding of the N-terminal region of smooth muscle caldesmon (CaD) to myosin and its C-terminal region to actin contributes to the inhibition of actin-filament movement over myosin heads in an in vitro motility assay. However, direct evidence for this assumption has been lacking. In this study, analysis of baculovirus-generated N-terminal and C-...

Matter accreting onto black holes may develop shocks due to the centrifugal barrier. A part of inflowing matter in the post-shock flow is deflected along the axis in the form of jets. Post-shock flow which behaves like a Compton cloud has ‘hot’ electrons emiting high energy photons. We study the effect of these ‘hot’ photons on the outflowing matter. Radiation from this region could accelerate ...

In this note, we present some ideas for describing the distributions of running maximum/minimum, first passage times and telegraphic meanders. Explicit formulae joint distribution extrema, number velocity switches terminal position are derived using coupled integral equations technique.

Mycoplasma pneumoniae is a major cause of bronchitis and atypical pneumonia in humans. This cell wall-less bacterium has a complex terminal organelle that functions in cytadherence and gliding motility. The gliding mechanism is unknown but is coordinated with terminal-organelle development during cell division. Disruption of M. pneumoniae open reading frame MPN311 results in loss of protein P41...