نتایج جستجو برای: tertiary amine

تعداد نتایج: 101914  

2016
Giorgos Koutoulogenis Nikolaos Kaplaneris Christoforos G Kokotos

Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In this review the synthesis of six-membered rings, that contain multiple chiral centers, either by a ring closing process or by a functionalization reaction on an already existing six-membered ring, utilizing bifunctional (thio)ureas will be...

Journal: :Bulletin of Pharmaceutical Sciences. Assiut 1985

The present study focused on stress corrosion cracking (SCC) and corrosion behavior of ferritic stainless steel (grade 430) in activated methyl diethanolamine (aMDEA) solution, which is classified as a tertiary amine. In this regard, cyclic polarization and U-bend tests were performed in CO2 loaded aMDEA with different concentrations at 25 and 70 °C to observe corrosion behavior and ...

Journal: :Molecular cancer therapeutics 2016
Patrick J Burke Joseph Z Hamilton Thomas A Pires Jocelyn R Setter Joshua H Hunter Julia H Cochran Andrew B Waight Kristine A Gordon Brian E Toki Kim K Emmerton Weiping Zeng Ivan J Stone Peter D Senter Robert P Lyon Scott C Jeffrey

A quaternary ammonium-based drug-linker has been developed to expand the scope of antibody-drug conjugate (ADC) payloads to include tertiary amines, a functional group commonly present in biologically active compounds. The linker strategy was exemplified with a β-glucuronidase-cleavable auristatin E construct. The drug-linker was found to efficiently release free auristatin E (AE) in the presen...

Journal: :Organic & biomolecular chemistry 2011
Wenjun Li Wenbin Wu Feng Yu Huicai Huang Xinmiao Liang Jinxing Ye

Catalytic asymmetric Michael additions with curcumin derivatives were achieved by a new series of tertiary amine-thiourea organocatalysts to afford the Michael adducts in high yields and excellent enantioselectivities.

Journal: :Organic & biomolecular chemistry 2006
Tian-Yu Liu Jun Long Bang-Jing Li Lin Jiang Rui Li Yong Wu Li-Sheng Ding Ying-Chun Chen

The bifunctional thiourea-tertiary amine derivatives of simple chiral diamines serve as highly enantioselective catalysts for the Michael addition of alpha-substituted cyanoacetates to vinyl sulfones, giving an efficient protocol for the construction of an all-carbon substituted quaternary stereocentre.

Journal: :Chemical communications 2014
Wei-Ming Gao Jin-Sheng Yu Yu-Lei Zhao Yun-Lin Liu Feng Zhou Hai-Hong Wu Jian Zhou

A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of plays an indispensable role in this reaction.

Journal: :Organic & biomolecular chemistry 2016
Bo-Xu Feng Bin Wang Xin Li

A highly enantioselective asymmetric addition reaction of thioglycolates and N-Boc aldimines was promoted by a bifunctional tertiary-amine squaramide catalyst. As a result, a number of chiral N,S-acetal derivatives were efficiently synthesized with good enantioselectivities.

Journal: :Organic & biomolecular chemistry 2012
Feng Pan Jian-Ming Chen Zhe Zhuang Yin-Zhi Fang Sean Xiao-An Zhang Wei-Wei Liao

The first tertiary amine-catalyzed multicomponent tandem Strecker-allylic-alkylation (SAA) reaction has been developed, which provides a facile access to functionalized α-amino nitriles, which could be readily converted into α-methylene-γ-butyrolactams.

2014
Laboni Ahsan M. Sarwar Jahan Iqbal Hassan Khan Larry Calhoun

The growing demand for rayon and cellulosic products has resulted in the conversion of a number of kraft pulp mills into dissolving pulp mills in recent years. In fact, kraft-based dissolving pulp production fits well into the concept of an integrated forest biorefinery, in particular, the utilization of dissolved organics in the pre-hydrolysis liquor (PHL) for bio-materials and bio-energy purp...

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