PURPOSE There has been little research on whether the knowledge that adolescents with epilepsy (AWE) or their family have about the condition reduces their perception of stigma. In this study we determine the relation between AWE's perceived stigma of, and knowledge about, epilepsy and maternal perception of stigma. METHODS This was a cross-sectional multicenter study involving AWE and their ...

1 Institute for Cardiovascular Prevention, Ludwig Maximilians University of Munich, Munich, Germany, 2 German Centre for Cardiovascular Research (DZHK), Munich Heart Alliance, Munich, Germany, 3 Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK, 4 BHF Centre for Excellence in Vascular Science and Medicine, College of Medical, Veterin...

OBJECTIVE To evaluate the association between the number of pharmacological inappropriateness and possible factors related with it. METHODS All polyphatological patients of the IMPACTO project in a tertiary hospital were included (July 2010-March 2012). The pharmacist performed the interventions based on a combined strategy that included the modified MAI and the STOPP-START criteria. A greate...

Unexpected and unprecedented directed remote lateral lithiation at one CH(CH3)2 of the 3-(2,6-di-isopropylphenyl) wingtip took place upon the reaction of functionalised N-heterocyclic carbene-type molecules with excess of LiCH2SiMe3, leading to dilithiated dianionic 4-amido-N-heterocyclic carbenes. DFT calculations show that the nature of the isolated species are under thermodynamic control.

A new and efficient approach to five- and six-membered benzannelated sultams by intramolecular C-arylation of tertiary 1-(methoxycarbonyl)methanesulfonamides under palladium catalysis is described. In case of the α-toluenesulfonamide derivative, an unexpected formation of a 2,3-diarylindole was observed under the same conditions.

OBJECTIVE To describe the profile of new drugs evaluated by the Pharmacy and Therapeutics committee in a tertiary hospital using a standardized tool, the Guideline for the Introduction of New Drugs in the Formulary (GINF form), as main objective. MATERIALS AND METHODS Retrospective observational study of drugs was assessed during 2008-2011. Variables related to the drug, the request, and the ...

Introduction. Mastalgia is a common breast condition among women referred to breast clinics worldwide. Whereas the prevalence is known in the Western world and Asia, the prevalence of the disease is unknown in many African countries. The aim of this study therefore was to determine the prevalence and describe factors associated with mastalgia among women attending a tertiary hospital in sub-Sah...

To determine the prevalence of Mycobacterium tuberculosis infection among dental patients and to assess dentists' risk for exposure, we conducted a study among dental patients at a large tertiary hospital in Nigeria, a country where tuberculosis is endemic. Ten (13%) of 78 sputum samples obtained were positive for M. tuberculosis.

We introduced a "Resident's guide to prescribing in eczema" in response to mounting residents' concerns with prescribing in dermatological conditions. This simple yet practical guide reduced prescription intervention rates significantly (7.6% from 86.7%) and was well-received by residents. Practical guides such as these are feasible educational tools to cultivate and establish proficient prescr...