OBJECTIVE Analyze whether testicular histologic patterns from a group of azoospermic men with varicocele is predictive of treatment outcome after subinguinal microsurgical varicocele repair. MATERIALS AND METHODS Seventeen azoospermic men underwent bilateral open single testis biopsy and microsurgical subinguinal repair of clinical varicoceles. RESULTS Histopathology of testicular biopsies ...

Spermatocytic seminoma (SS) is a rare testicular neoplasm characterized by a palpable, painless, slowly enlarging mass in the testis. Even more rare is a synchronous bilateral presentation. Only eight cases of bilateral SS have been reported in the literature, of which three cases were present with synchronous testis enlargement, and five were sequential. Here, we report an additional case of s...

Leydig cell tumor (LCT) is a rare tumor of the male testicular interstitium. This article provides an overview of the major pathologic manifestations of LCT of the testis; patient characteristics; clinical, radiologic, and laboratory features; prognosis; and management. LCTs of the testis are frequently hormonally active, leading to either feminizing or virilizing syndromes. The tumor is usuall...

A complex interplay between schistosomiasis and function of different organs leads to the impairment of these organs. In this study, we demonstrated the protective effect of berberine chloride (BER) in schistosomiasis-inducted oxidative stress on renal and testicular tissues of mice compared to praziquantel (PZQ). Lipid peroxidation (LPO), nitric oxide (NO), glutathione (GSH), superoxide dismut...

AIM To evaluate the immunohistopathological changes in the contralateral testis of rats after an experimental spermatic cord torsion. METHODS Male Sprague-Dawley rats of 45-50 days old were subjected to a 720 degree unilateral spermatic cord torsion for 10, 30 and 80 days (experimental group, E), respectively or sham operation (control group, C). Histopathology of the contralateral testis as ...

The objective of this study was to investigate the effect of high and moderate summer ambient temperatures on testicular structures and endocrine profile of developing ram lambs. Twenty fall-born ram lambs were randomly divided into two groups: animals were kept outdoor (n=10) under ambient temperature (31-50 degrees C) or maintained indoor (26-32 degrees C) from May to October 2007. Daily maxi...

Chlorpirifos (CPF) is a widely used organophosphate insecticide for both agricultural and domestic purposes with attendant human exposures. Many authors have documented the toxic effects of CPF on the central nervous system. This study was designed to study the effect of CPF and the influence of coadministration of ascorbic acid (AA) on the testicular functions of albino rats. Twenty five 2 mon...