Background: Male infertility is responsible for approximately 50% of infertility in the world. Reactive oxygen species (ROS) is one of the causative agents of infertility in males which effects on sperm quality and function. In this study, the effects of oxidative stress induced by tertiary-butyl hydroperoxide (TBHP) were investigated on sperm quality, testis tissue and miRNAs expression. Mater...

One of the rarest varieties of intrascrotal neoplasm is a tumor composed of striated muscle. Only a few cases have been published and most of these appear as isolated reports in the older foreign literature. In many cases, the tumor was closely connected with the testicle, but it was difficult to determine whether it arose from the testis or from the adjacent tissue. Rokitansky in 1849 describe...

The role of breast cancer resistance protein (BCRP/ABCG2) in limiting the brain and testis penetration of xenobiotic compounds in the blood-brain and -testis barriers was investigated using Bcrp(-/-) mice. Tissue/plasma concentration ratios in the brain (K(p,brain)) and testis (K(p,testis)) obtained under steady-state conditions were significantly increased in Bcrp(-/-) mice for PhIP (2-amino-1...

Xanthogranulomatous epididymitis is a rare benign process with destruction of tissue and replacement by cellular infiltration foamy macrophages, dense lymphocytes plasma cells. Literature has very few case reports. We reported here 72 years old male who presented as scrotal abscess bilateral hydrocele on ultrasound. On exploration he had normal right testis localized to epididymis underwent epi...

Case Description- A seven-year-old male donkey was admitted with a history of left scrotal swelling with ulcerating wound since 2 years.Clinical Findings- The left scrotum was painful. There was ulcerating and hypergranulating wound discharging bloody discharge. The wall of the scrotum was found thick and infiltratedwith soft slimy non capsulated and lobulated fibrous tissue masses. The left te...

objective(s) in recent years concerns have been raised regarding the incidence of male reproductive disorders from exposure to endocrine disruptors. so, chronic effects of di(2-ethylhexyl)phthalate were studied on histological and stereological structure of testis in adult wistar rats. materials and methods thirty two adult wistar rats were randomly divided in four equal experiment groups; oil ...

background & aim: onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. however, burn healing effect of this herb has not been yet reported in pharmaceutical texts. the aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type ii burns of back and testis region in wistar rats. experimental: a total of 24 r...

The effect of testicular binding of human chorionic gonadotropin upon the biological activities of the hormone was examined by comparison of the binding and activation properties of (125)I-labeled gonadotropin before and after binding to rat testis in vitro. Biologically active (125)I-gonadotropin taken up by rat testis was dissocated from testis binding-sites at low pH and evaluated for its ab...

BACKGROUND Testicular torsion due to oxidative stress results in infertility and testicular damage which can be preventable an important health problem worldwide. AIM The purpose of the present study was to investigate the changes of malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS) levels; histopathological alterations; morphology, concentration and motilities...