Neocarzinostatin, a new polypeptide which had shown antitumor activity in animals, was given to 17 patients with advanced malignant tumors. Five of 17 patients showed objective regression of tumors and disappearance of clinical symptoms. On account of the limited clinical experiences, no assertion can be made as to the range of therapeutic indication or to the comparison of neocarzino statin wi...

The de-novo formation of vessels (angiogenesis) and the remodelling of preexisting collateral vessels (arteriogenesis) are processes that occur naturally in ischemic heart disease. Promoting these processes by administration of various substances or other physical stimuli (therapeutic angiogenesis) may provide a future strategy for the treatment of ischemic vascular diseases. Mechanisms of angi...

acceptance and commitment therapy (act) is a new development within behavioral therapy. its goal is to promote psychological flexibility. numerous studies show that suffering results when people attempt to avoid their inner experiences (experiential avoidance). this experiential avoidance often leads to rigid and inflexible behavior that also leads them to compromise their goals and what is imp...

ayurveda, the indian art of holistic medicine describes fasting in terms of upavasa and considers it as one among the depletion therapies.   besides the extensive explanations on the preventive purports of fasting, the classics have explicitly explained and exemplified the therapeutic importance of fasting while treating different diseases and dealing with different stages of the diseases. feve...

conclusions it is better to remove the unused devices safely to prevent and decrease their possible complications. case presentation a 50-years-old woman, with a history of breast cancer, had a permcath emplacement in right subclavian vein for a course of chemotherapy. the treatment for cancer seemed to be successful and the permcath had remained in its position without complication, for a coup...

Abstract Acinetobacter baumannii infections pose a grave risk to hospitalized patients due their resistance antimicrobial substances. This necessitates the urgent development of novel therapeutic strategies. By comparing genetic repertoire between pathogenic and non-pathogenic we discovered traits that offer surprising insights into how pathogen interacts with humans. However, much remains be l...

We report the concentrations of scheduled prescription drugs in blood samples from people arrested in Sweden for driving under the influence of drugs (DUID). The investigation covered a 2 year period 2004 (N = 7052 cases) and 2005 (N = 7759 cases) and was prompted by recent legislation stipulating zero-concentration limits in blood for controlled substances. However, prescription drugs are exem...

ayurveda, manoeuvres mankind to head a healthy life in order to pursue four-fold bliss. with a view to combat physical and mental annoyances, classics have explicated two-fold therapeutic modalities; langhana/depletion and brihmana/nourishing. upavasa /fasting is one among ten depletion therapies explained. it is envisioned at all three levels of ayurvedic therapies- rational/objectively planne...

cardiovascular diseases are the most common causes of human morbidity and mortality despite significant therapeutic improvements by surgical or pharmacological approaches in the last decade. micrornas (mirnas) have a significant role in diseases development or response to treatment. in this review, we summarized the role of mirnas in the pathogenesis or the treatment of coronary artery disease ...