نتایج جستجو برای: therapeutic substitution
تعداد نتایج: 407128 فیلتر نتایج به سال:
The biopharmaceutical market is driven by the steady increase in demand for therapeutic proteins produced in mammalian cells. Glutamine is a main nitrogen source and also a main energy source with glucose in mammalian cell cultures for therapeutic protein production. As a result of glutamine metabolism and the natural decomposition of glutamine, ammonia, which is known to negatively affect cell...
despite the body of research on textbook evaluation from the discourse analysis perspective, cohesive devices have rarely been analyzed in english for specific purposes (esp) textbooks. the acquisition and use of cohesive devices is inherent to naturalistic communication, including business interactions. hence, l2 learners of business english should be exposed to these devices through cohesion-...
The effect of monochloro and dichloro substitution into the ethyl portion on the pyrolysis of ethyl vinyl ether has been studied. This involved four possible monosubstituted derivatives and six disubstituted derivatives. For the monochloro derivatives, B- chloro substitution enhanced the rate constant while a- chloro substitution depressed it noticeably. For the dichloro derivatives, substi...
چکیده ندارد.
The anxiety-reduction model often utilized to explain initiation and perpetuation of episodic drinking was found inadequate to explain motivation for alcohol use by the alcoholic. Euphoria and elation were manifest only during the initial phases of intoxication. Prolonged drinking was characterized by progressive depression, guilt, and psychic pain. These unpleasant affects, however, were poorl...
Although humanized antibodies have been highly successful in the clinic, all current humanization techniques have potential limitations, such as: reliance on rodent hosts, immunogenicity due to high non-germ-line amino acid content, v-domain destabilization, expression and formulation issues. This study presents a technology that generates stable, soluble, ultrahumanized antibodies via single-s...
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