To the Editor: We have read with great interest the recently published article by Gerber et al. (1) on the potential endometrial benefit of anastrozole given to postmenopausal breast cancer patients with tamoxifen-induced endometrial pathology. Their study showed that the switch to anastrozole significantly reduced the need for a second invasive gynecologic procedure for recurrent vaginal bleed...

Background: In spite of the great deal of research in assisted reproductive techniques, more than 80% of transferred embryos by IVF/ICSI methods fail to be implanted. The causes for repeated implantation failures (RIF) may be reduced endometrial receptivity or other various uterine pathologies, such as thin endometrium, altered expression of adhesive molecules or immunological factors; whereas ...

In order to explore the impact of endometrial thickness on hCG administration day on ongoing pregnancy rate (OPR) in IVF-ET cycles, we retrospectively analyzed data from 10,406 patients undergoing their first IVF cycles with standard gonadotropin releasing hormone analogue (GnRH-a) long protocol. Firstly, patients were divided into poor (≤ 5 oocytes), medium (6-14 oocytes), and high (≥ 15 oocyt...

Background: Endometrial thickness is one of the major factors for a receptive endometrium and successful implantation. Thin endometrium, generally measuring <7 mm are thought to be less able support implantation pregnancy. Several adjuvants have been investigated their efficacy on thin in assisted reproductive technology. Granulocyte colony stimulating factor (G-CSF) glycoprotein that promot...

Abstract Study question Is thin endometrium (<6 mm) associated to an abnormal receptivity status? Summary answer Thin is significantly with a displaced WOI. What known already The measurement of endometrial thickness by 2D vaginal ultrasound (US) routine practice in Assisted Reproduction Techniques (ART). poor reproductive outcome; however, the potential reason unknown. design, size, dur...