نتایج جستجو برای: three conceptual continuous rainfallrunoff models hbv

تعداد نتایج: 2359041  

2015
Perrine Martin Clarisse Dubois Emilie Jacquier Sarah Dion Maryline Mancini-Bourgine Ophélie Godon Roland Kratzer Karine Lelu-Santolaria Alexei Evlachev Jean-François Meritet Yasmin Schlesinger Dominique Villeval Jean-Marc Strub Alain Van Dorsselaer Jean-Baptiste Marchand Michel Geist Renée Brandely Annie Findeli Houda Boukhebza Thierry Menguy Nathalie Silvestre Marie-Louise Michel Geneviève Inchauspé

OBJECTIVE To assess a new adenovirus-based immunotherapy as a novel treatment approach to chronic hepatitis B (CHB). METHODS TG1050 is a non-replicative adenovirus serotype 5 encoding a unique large fusion protein composed of a truncated HBV Core, a modified HBV Polymerase and two HBV Envelope domains. We used a recently described HBV-persistent mouse model based on a recombinant adenovirus-a...

1995
Jesus Savage-Carmona Alistair Holden Mark Billinghurst

In this paper we show how symbolic Artii-cial Intelligence (AI) techniques can be combined with traditional Digital Signal Processing (DSP) and statistical methods to enhance speech recognition. We implement a hybrid system which uses a rule-based expert system to create a Conceptual Dependency (CD) representation of the spoken input. Conceptual Dependencies are used for natural language unders...

Journal: :Cognition 2018
Ardi Roelofs

Computational models of lexical selection in spoken word production have been applied to semantic interference effects in picture naming response times obtained with continuous naming, blocked-cyclic naming, and picture-word interference paradigms. However, a unified computational account of the effects in the three paradigms is lacking. Here, I show that the inclusion of conceptual bias in the...

Journal: :iran agricultural research 2010
a. izady b. ghahraman k. davari

hysteresis has been widely recognized in the soil water relationship. in this paper, a detailed review of hysteresis was performed in relation to its models. so far, different models have been suggested to describe hysteresis in the water retention curve (wrc) that could be categorized into two main groups: conceptual and empirical models. the models in the first group are based on the domain t...

2016
Shun Kaneko Sei Kakinuma Yasuhiro Asahina Akihide Kamiya Masato Miyoshi Tomoyuki Tsunoda Sayuri Nitta Yu Asano Hiroko Nagata Satoshi Otani Fukiko Kawai-Kitahata Miyako Murakawa Yasuhiro Itsui Mina Nakagawa Seishin Azuma Hiromitsu Nakauchi Hironori Nishitsuji Saneyuki Ujino Kunitada Shimotohno Masashi Iwamoto Koichi Watashi Takaji Wakita Mamoru Watanabe

Hepatitis B virus (HBV) is not eradicated by current antiviral therapies due to persistence of HBV covalently closed circular DNA (cccDNA) in host cells, and thus development of novel culture models for productive HBV infection is urgently needed, which will allow the study of HBV cccDNA eradication. To meet this need, we developed culture models of HBV infection using human induced pluripotent...

2014
Tadashi Inuzuka Ken Takahashi Tsutomu Chiba Hiroyuki Marusawa

Hepatitis B virus (HBV) infection is one of the most prevalent infectious diseases associated with various human liver diseases, including acute, fulminant and chronic hepatitis; liver cirrhosis; and hepatocellular carcinoma. Despite the availability of an HBV vaccine and the development of antiviral therapies, there are still more than 350 million chronically infected people worldwide, approxi...

Journal: :World journal of gastroenterology 2011
Zhen-Zhen Zhang Xiang Liu De-Qiang Wang Mai-Kun Teng Li-Wen Niu Ai-Long Huang Zhi Liang

AIM To study Hepatitis B virus (HBV) infection and its association with hepatocellular carcinoma (HCC) at the miRNA level. METHODS Three cellular models were used to investigate miRNA expression changes during HBV infection: human HepG2 hepatoblastoma cell line as a model without HBV infection; HepG2 cell line transfected with a 1.3-fold full-length HBV genome as an acute infection model; and...

2018
Alessandro Miglietta Chantal Quinten Pier Luigi Lopalco Erika Duffell

Hepatitis B prevention in European Union/European Economic Area (EU/EEA) countries relies on vaccination programmes. We describe the epidemiology of acute hepatitis B virus (HBV) at country and EU/EEA level during 2006-2014. Using a multi-level mixed-effects Poisson regression model we assessed differences in the acute HBV infection notification rates between groups of countries that started un...

Journal: :iranian journal of fuzzy systems 2005
j. j. buckley k. d. reilly l. j. jowers

in previous studies we first concentrated on utilizing crisp simulationto produce discrete event fuzzy systems simulations. then we extendedthis research to the simulation of continuous fuzzy systems models. in this paperwe continue our study of continuous fuzzy systems using crisp continuoussimulation. consider a crisp continuous system whose evolution depends ondifferential equations. such a ...

Journal: :Archives of disease in childhood 1991
H Shimizu T Mitsuda S Fujita S Yokota

To investigate the infectivity of hepatitis B virus (HBV) from mothers to their newborn offspring, HBV-DNA in plasma and peripheral mononuclear cells from 28 antihepatitis Be positive, hepatitis B surface antigen positive carrier mothers was examined by a highly sensitive polymerase chain reaction/Southern hybridisation technique. HBV specific DNA was detected in three maternal mononuclear cell...

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