background: children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. the aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. p...

mental stress and daily crises comprise a part of physical and mental threats. perceived stress is a physical and mental threat, as well. perceived stress is a psychological process during which the individual considers his/ her physical and psychological welfare as being threatened. since idiopathic thrombocytopenic purpura (itp) is one of the chronic diseases being able to affect patients' pe...

Wiskott-Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott-Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital for purpura and thrombocytopenia. His mean platelet volume was reported to be normal. Treatment with intravenous immunoglobulins failed to imp...

The article analyzes a clinical case of the development thrombotic thrombocytopenic purpura (TTP) in patient with verified COVID-19 infection. algorithm TTP diagnosis when ADAMTS13 biomarker test is unavailable presented. presents scheme effective treatment use plasma exchange, methylprednisolone and rituximab administration.

Objective: Thrombotic thrombocytopenic purpura (TTP) is the most malignant variant of microangiopathy that usually presents by typical symptoms including thrombocytopenia, hemolytic anemia, neurological abnormalities, fever and renal impairment. Report of the Case: We report a 12-year-old male presented by cytopenia, fever, purpura on his extremities, seizure and lethargy. Peripheral blood sm...

It is well known that idiopathic thrombocytopenic purpura occurs most commonly during childhood but its incidence is difficult to estimate. MacFarlane (1960) found that in 737 cases 45 per cent were aged 15 years and younger, while Wintrobe (1956) noted that in childhood purpura was most frequent between the ages of two and eight years. The disease is uncommon in the general population. The pre...

CONTEXT Pancreatic adenocarcinoma presenting as idiopathic thrombocytopenic purpura has not been previously reported in the literature. CASE REPORT A newly diagnosed patient with metastatic pancreatic adenocarcinoma developed thrombocytopenic purpura prior to initiation of chemotherapy. Generalized petechiae were present and peripheral smear revealed giant platelets. Drug induced and other th...

Untreated human immunodeficiency virus (HIV) can be complicated by opportunistic infections, including disseminated histoplasmosis (DH). Although endemic to portions of the United States and usually benign, DH can rarely act as an opportunistic infection in immunocompromised patients presenting with uncommon complications such as acute kidney injury and idiopathic thrombocytopenic purpura. We r...

A case of thrombotic thrombocytopenic purpura in a patient with a recent flare of cerebral lupus is presented. The patient presented with neurologic symptoms, pyrexia, thrombocytopenia and leucocytosis. Following initial investigation, imaging of brain and negative microbiology, a diagnosis of cerebral lupus was made and appropriately treated. After a stable period oftwo weeks, deterioration in...

A 27 year old housewife developed thrombotic thrombocytopenic purpura during the twelfth week of pregnancy. She had partial response to initial plasma infusion and subsequent plasmapheresis. However, her clinical course was complicated by the development of severe pancytopenia the consequence of a hypocellular marrow. She succumbed to septicaemic shock one month after diagnosis. The development...