Systematic administration of interferon-alpha (INF-alpha) is considered as the backbone of HCV therapy since 1991. Interferon (IFN) therapy can cause vasculitis, glomerulonephritis, cryoglobulinemia and certain other autoimmune diseases such as sialoadentitis, lichen planus and thyroiditis. Related to the factors of interferons, extensively studied gland is thyroid gland. A strong association w...

Hypercalcitoninemia has frequently been reported as a marker for medullary thyroid carcinoma. Currently, calcitonin measurements are mostly useful in the evaluation of tumor size and progression, and as an index of biochemical improvement of medullary thyroid carcinomas. Although measurement of calcitonin is a highly sensitive method for the detection of medullary thyroid carcinoma, it presents...

OBJECTIVE After thyroidectomy hypocalcaemia is the most significant complication for clinicians. In this study, we investigated the factors associated with development of hypocalcaemia after thyroidectomy. MATERIALS AND METHODS We investigated the patients prospectively for age, gender, preoperative diagnosis, hormonal status, operative time, operating surgeon, existence of parathyroid gland ...

Thyroid hormones are important at cellular level, affecting nearly every type of tissue in the body. Objectives: The present study was carried out to determine whether thyroid hormones affect lipid profile in patients with hyperthyroidism. Materials and Methods: This study was carried out on 20 hyperthyroid patients (10 men and 10 women) with mean age 48.5+13.1 years and 22 apparently healthy c...

Resistance to thyroid hormone (RTH) is a rare disorder characterized by variable tissue hyporesponsiveness to thyroid hormone, usually caused by mutations in the thyroid hormone receptor beta (TRβ). It has been reported that the serum of patients with RTH is free of auto-antibodies against thyroglobulin (Tg) and thyroid peroxidase (TPO), except in rare cases where coincidental autoimmune thyroi...

Introduction Certain individuals and families seem to be unusually prone to develop organ-specific autoimmune disorders. The conditions which appear most closely associated are thyroid disease (Hashimoto's thyroiditis, thyrotoxicosis or primary hypothyroidism), Addison's disease, hypoparathyroidism and pernicious anaemia. A number of other conditions may also be associated including diabetes me...

PURPOSE To examine the association of personal values, the built environment, and auto availability with walking for transportation. SETTING Participants were drawn from 11 U.S. metropolitan areas with good transit services. SUBJECTS 865 adults who had recently made or were contemplating making a residential move. MEASURES Respondents reported if walking was their primary mode for nine tr...

Studies on the impact of subclinical hypothyroidism in infertility are scarce and this seeks to determine the proportion of infertile Nigerian women with hyperprolactinaemia that had subclinical hypothyroidism. Serum prolactin and thyroid stimulating hormone were determined using ELECSYS 1010 auto analyzer. Two hundred infertile women were evaluated and 67(33.7%) had hyperprolactinaemia. Subcli...