The established function of thyroid stimulating hormone (TSH) is to promote thyroid follicle development and hormone secretion. The osteoporosis associated with hyperthyroidism is traditionally viewed as a secondary consequence of altered thyroid function. We provide evidence for direct effects of TSH on both components of skeletal remodeling, osteoblastic bone formation, and osteoclastic bone ...

Twelve males with fragile-X syndrome between the ages of three and 28 years underwent assessment of thyroid function. All 12 subjects demonstrated normal baseline values for thyroid stimulating hormone (TSH), thyroxine, thyroid binding globulin (TBG), and estimated free thyroxine (EFT). Relative to a control group reported in the literature, however, the fragile-X subjects exhibited a blunted T...

Graves's disease (diffuse toxic goitre) Toxic nodular goitre Multinodular (Plummer's disease) Uninodular (toxic adenoma) Nodular goitre with Graves's disease Excess thyroid stimulating hormone Pituitary tumour Choriocarcinoma and hydatidiform mole Embryonal testicular carcinoma Other malignancy (?) Extraneous thyroid hormone Exogenous: Intentional factitious Overenthusiastic therapy During T-3 ...

A thyroid disease is a medical condition impairing the function of the thyroid. The thyroid hormones act on nearly every cell in the body. Imbalance in production of thyroid hormones arises from dysfunction of the thyroid gland itself, the pituitary gland, which produces thyroid-stimulating hormone (TSH), or the hypothalamus, which regulates the pituitary gland via thyrotropin-releasing hormone...

A thyroid disease is a medical condition impairing the function of the thyroid. The thyroid hormones act on nearly every cell in the body. Imbalance in production of thyroid hormones arises from dysfunction of the thyroid gland itself, the pituitary gland, which produces thyroid-stimulating hormone (TSH), or the hypothalamus, which regulates the pituitary gland via thyrotropin-releasing hormone...

BACKGROUND Hashimoto's thyroiditis is the most common endocrinopathy in premenopausal women, and is associated with various gynecological problems, including recurrent miscarriage and unexplained infertility. A possible influence of Hashimoto's thyroiditis on the success of intrauterine insemination seems likely, but has not been evaluated as yet. Therefore, the aim of our study was to retrospe...

The subunits, cy and /3, of human thyroid-stimulating hormone (TSH) from the pituitary have been obtained by the same procedures utilized for the preparation of bovine TSH subunits, namely, dissociation in 1 M propionic acid and separation by gel filtration. The amino acid composition of human TSH-(r indicates that this subunit is identical or nearly so with the CY subunits of human luteinizing...

congenital hypothyroidism is a condition of thyroid hormone deficiency. approximately 1 in 4000 newborn infants has a deficiency of thyroid function. the aim of this study is determination of the prevalence of permanent and transient congenital hypothyroidism (ch) in yazd, iran.from may 2006 to june 2008, 35377 newborns were screened by measuring serum tsh obtained by heel prick. the neonates w...

We examined sera submitted for autoantibody testing for thyroid microsome antibodies (TMA), elevated thyroid-stimulating hormone (TSH), and free thyroxine concentrations. The frequency of TMA in antinuclear antibody-positive sera was higher (19%) than that in antinuclear antibody-negative sera (12%). Elevated TSH concentrations in serum and subnormal thyroxine concentrations in serum were assoc...