background and aims. the aim of the present study was to compare the inhibitory effects of two systemic doses of hesa-a on prevention of 4-nqo-induced tongue neoplasms in rats. this study evaluated weight and histopathological changes. materials and methods. forty-eight male sprague dawley rats were divided into four groups of a, b, c and d of each 12 rats. the rats in groups b to d received 30...

INTRODUCTION Granular cell tumor is an uncommon neoplasm that can occur in any part of the body, including the orofacial region. The tumor is usually benign, but there are reports of cases in which the tumor shows a locally aggressive behavior, malignancy, and distant metastases. The most widely accepted hypothesis is that granular cell tumor arises from the altered metabolism of Schwann cells....

Tuberculosis of the tongue is a very rare event even in areas and countries in which tuberculosis is endemic. The disease can present itself in a variety of clinical appearances, most of which may mimic malignant lingual neoplasms clinically. In this case, we present a patient who initially complained of an ulcerated lingual swelling, which was suspected to be a squamous cell carcinoma on clini...

objectives: geographic tongue or migratory glossitis is an inflammatory disorder with unknown etiology. considering the accompanied burning pain, taste dysfunction, and lack of definite cure, it is important to treat this condition symptomatically. the objective of the current study was to compare the efficacy of a combination of 0.05% retinoic acid and 0.1% triamcinolone acetonide with that of...

As tongue cancer is one of the major malignant cancers in the world, understanding the mechanism of maintenance of lingual epithelial tissue, which is known to be the origin of tongue cancer, is unquestionably important. However, the actual stem cells that are responsible for the long-term maintenance of the lingual epithelium have not been identified. Moreover, a simple and convenient culture ...

BACKGROUND Tongue tumour thickness has been shown to have a correlation with neck nodal metastasis and hence patient survival. Current AJCC guidelines recommend inclusion of tongue tumour thickness measurement in routine radiologic staging. Several studies have attempted to define the accuracy of MRI in measuring tongue tumour thickness. The aim of our study was to compare tongue tumour thickne...

a set of one hundred and twenty nine patients with known primary malignancy and suspected brain metastasis was reviewed in present study. the patients were selected among patients presented to the mri section of imam khomeini hospital or a private mri center in tabriz (iran). primary tumor site, clinical manifestations, number and site of lesions were identified in this patient population. the ...

introduction tongue is one of the most important organs in the oral cavity which has significant roles in different functions such as speaking, mastication, swallowing, breathing, etc. the tongue may be influenced by internal diseases sooner than other organs and also may be involved in some abnormalities that some are developmental and some of them are genetical and environmental. this study h...

Background: Acinic cell carcinoma (ACC) is a relatively rare and slowly growing tumor of the major salivary glands, usually arising from the parotid and rarely from the submandibular and sublingual salivary glands. ACC accounts for 3 to 4% of parotid tumors, 2 to 6% of all salivary gland tumors and 10 to 17% of all malignant salivary gland tumors. Case report: A 40-year-old woman reported a slo...