An online survey of members of the American Society of Cataract and Refractive Surgery indicated a strong preference for preoperative and postoperative topical antibiotic prophylaxis, with most surgeons favoring latest generation topical fluoroquinolones. A significant percentage of surgeons reported being concerned about the risks of homemade intracameral antibiotic preparations, and there was...

We generated a list of all topical corticosteroids available in Poland in 2015 (2) and described by the manufacturer as being ‘for topical use on the skin’. For each product meeting the inclusion criteria, the list of ingredients was extracted from the package insert. Subsequently, the compounds were matched against the European baseline series of 28 contact allergens (3) and possible cross-rea...

• 2 6 7 H O S P I TA L P H A R M AC I S T Pluronic lecithin organogel (PLO), a base in which drugs can be incorporated, is currently generating great interest in the US as a topical and transdermal drug delivery vehicle. Compounding pharmacists are advertising the vehicle, as well as their compounding services, and a large number of drugs have already been incorporated within PLO for human and ...

Ageing skin is characterized by fine lines, wrinkles, lentigines, dyspigmentation and increased coarseness. Topical preparations alleged to combat these changes abound in the over-the-counter market. Some of the most popular ingredients used in these products are vitamins, minerals and botanical extracts. Proposed mechanisms for antiageing effects on skin range from antioxidant properties to im...

Dysbiotic shifts in intestinal and pharyngeal microflora were studied in 22 normal volunteers in 9-, 14-, 105- and 520-d chamber experiments simulating some of the spaceflight factors. Two preparations were administered to prevent pharyngeal and intestinal dysbiosis: oral dry probiotic based on indigenous intestinal Enterococci and topical collagen-immobilized Lactobacterin based on indigenous ...

We assessed the frequency of, reasons for and the most common dermatological problems resulting from misuse of topical corticosteroids. We used a questionnaire and skin examination to study patients presenting at the dermatological centre, AI-Sadr Teaching Hospital, Al-Najaf, Iraq during the period March 2001-April 2002. Of 1780 new patients, 140 (7.9%) had misused topical corticosteroids. Abou...

Resorcinol, also known as resorcin (1,3-dihydroxybenzene; CAS no. 108-46-3), is an important ingredient of Castellani’s paint solution, an antifungal preparation that is commonly used in daily dermatological clinical practice. Apart from its use in hair dyes, resorcinol is also used in several other topical preparations, because of its antipruritic, keratolytic and antimycotic properties. Sodiu...

of the hair follicles) and differentiates it from the other conditions.5 Histology of tissue obtained by curettage of a papule is sufficient to establish the definitive diagnosis. Although there are reports of GP that resolved spontaneously once the irritant was eliminated, the lesions usually persist. A number of therapeutic modalities, including topical and oral preparations of retinoids, vit...

The medicated lacquer preparations are generally used in fungal diseases. Use of this system avoids oral toxicity of anti fungal drugs. The main challenge associated with developing nail lacquers for the treatment of nail disorders is to deliver the active concentration to the site of infection. Penetration of topical antifungal through the nail plate requires a vehicle that is specially formul...

This paper deals with two patients on warfarin in whom the use of topical methylsalicylate preparations led to clinically significant bleeding problems. The first patient required fresh frozen plasma to tide over the crisis while the second patient recovered spontaneously on stopping the warfarin temporarily. The possible mechanisms by which salicylates potentiate the anticoagulant effect of wa...