background: breast cancer is one of the most prevalent malignancies among women in various countries. her2 overexpression, which is due to different reasons, occurs in 20-30% of breast cancers. her2 gene encodes an 185kda transmembrane glycoprotein with 1255 amino acids. this active product triggers downstream intracellular signaling pathways inducing cell proliferation and cell survival. these...

abstract having no exact knowledge of most appropriate harvesting time in kiwifruit grown in different regions of guilan province, as well as the low storage longevity of the fruits are the most important factors causing considerable reduction in both marketability and export affairs. in this study, the influence of fruit quality in term of harvesting time on the postharvest quality and food va...

Traditional supply chain inventory modes with trade credit usually only assumed that the up-stream suppliers offered the down-stream retailers a fixed credit period. However, in practice the retailers will also provide a credit period to customers to promote the market competition. In this paper, we formulate an optimal supply chain inventory model under two levels of trade credit policy with d...

In this study, a two-echelon supplier-manufacturer system with finite production rate and lead time is proposed. It is assumed that shortage is not permitted and the lot size of manufacturer (second echelon) is m-factors of the lot size of supplier (first echelon) and supplier can supply the manufacturer’s lot size in several shipments in each cyc...

Stochastic variation in cell cycle time is a consistent feature of otherwise similar cells within a growing population. Classic studies concluded that the bulk of the variation occurs in the G1 phase, and many mathematical models assume a constant time for traversing the S/G2/M phases. By direct observation of transgenic fluorescent fusion proteins that report the onset of S phase, we establish...

Exergy analysis of an integrated molten carbonate fuel cell-turbo expander-steam turbine hybrid cycle has been presented in this study. The proposed cycle has been used as a sustainable energy approach to provide a micro hybrid power plant with high exergy efficiency. To generate electricity by the mentioned system, an externally reformed molten carbonate fuel cell located upstream of the combi...

The dater equalities constitutes an appropriate tool which allows a linear description of Timed Event Graphs in the field of (max, +) algebra. This paper proposes an equivalent model in the usual algebra which can describe Timed and P-time Event Graphs. Considering 1-periodic behavior, the application of a variant of Farkas’ lemma allows the determination of upper and lower bounds of the produc...