The BioBreeding- Diabetes Prone (BB-DP) rat spontaneously develops an autoimmune diabetic syndrome that is dependent on the RT1 u Major Histocompatibility Complex (MHC) haplotype and homozygosity for an allele at the Lymphopenia (Lyp) locus. Lyp mutation is responsible for a peripheral T -lymphopenia. There are other genetic loci contributing to diabetes susceptibility in this strain. BB ra...

[1] The presence of chlorine radical species in the lower troposphere has been postulated, but only indirect evidence of its existence has been reported.We present the first direct spectroscopic observations of up to 15 ± 2 pmoles/mole-air chlorine oxide (ClO) in the mid-latitude boundary layer and confirm a previous discovery of the existence of bromine oxide (up to 6 ± 0.4 pmoles/mole-air BrO...

Maternal hypothyroidism during pregnancy impairs brain function in human and rat offspring, but little is known regarding the influence of maternal hyperthyroidism on neurodevelopment. We have previously shown that the expression of neuronal and glial differentiation markers in fetal brain is compromised in hypothyroid rat dam pregnancies and have now therefore extended this investigation to hy...

Halogens are volatile elements present in trace amounts the Earth’s crust, mantle, and core. They show behavior tend to be incompatible except for fluorine, which makes them key tracers of fluid-mediated and/or melt-mediated chemical transport processes. Even small quantities halogens can profoundly affect many physicochemical processes such as melt viscosity, temperature stability mineral phas...

We present comparison of X-ray proxies for the total cluster mass, including the spectral temperature (TX), gas mass measured within r500 (Mg), and the new proxy, YX, which is a simple product of TX and Mg and is related to the total thermal energy of the ICM. We use mock Chandra images constructed for a sample of clusters simulated with the eulerian N-body+gasdynamics adaptive mesh refinement ...