CONTEXT Basic research and observational studies suggest vitamin E or vitamin C may reduce the risk of cardiovascular disease. However, few long-term trials have evaluated men at initially low risk of cardiovascular disease, and no previous trial in men has examined vitamin C alone in the prevention of cardiovascular disease. OBJECTIVE To evaluate whether long-term vitamin E or vitamin C supp...

BACKGROUND In-hospital hypovitaminosis C is highly prevalent but almost completely unrecognized. Medical awareness of this potentially important disorder is hindered by the inability of most hospital laboratories to determine plasma vitamin C concentrations. The availability of a simple, reliable method for analyzing plasma vitamin C could increase opportunities for routine plasma vitamin C ana...

objective: streptozotocin (stz) destroys the beta cells of pancreas by generation of reactive oxygen species and vitamin c has documented antioxidant properties. this study was designed to evaluate the preventive effect of supplementation of diet by vitamin c on induction of stz-diabetes and its effect on carbohydrate and lipid metabolism of diabetic rats. materials and methods: fifty male wist...

Background: Bisphenol A (BPA), an estrogenic environmental contaminant is also known for oxidative stressinducing effect. The aim of this study was to investigate the effect of vitamin C as an antioxidant on the ovary tissue in adult rats treated with BPA. Materials and Methods: Adult female rats (200 ±20 g) were divided into 4 groups (n=6):control, bisphenol A (60μg/Kg/day) , vitamin C (150 mg...

A 60-days growth trial was conducted in a flow-through culture system to examine the effects of different dietary vitamin C and iron levels on the growth, hematological and immunological parameters of rainbow trout (Oncorhynchus mykiss) fingerlings (with average initial weight of 5.12 ± 0.02 g). Three levels of vitamin C (150, 200 and 250 mg kg-1 diet) and iron (5, 7 and 9 mg kg-1 diet) (as fer...

Processed fruits and vegetables have been long considered to have lower nutritional value than their fresh commodities due to the loss of vitamin C during processing. This research group found vitamin C in apples contributed < 0.4% of total antioxidant activity, indicating most of the activity comes from the natural combination of phytochemicals. This suggests that processed fruits and vegetabl...

INTRODUCTION The ethiopathogenesis of tympanosclerosis has not been completely under- stood yet. Recent studies have shown that free oxygen radicals are important in the formation of tympanosclerosis. Melatonin and Vitamin C are known to be a powerful antioxidant, interacts directly with Reactive Oxygen Species and controls free radical-mediated tissue damage. OBJECTIVE To demonstrate the pos...

Antioxidant vitamins have been reported to be associated with an improvement in blood lipid profiles, but results are not consistent. The present study was designed to determine whether long-term vitamin C supplementation could alter serum lipid concentrations in subjects who completed a 5-year population-based double-blind intervention trial. A total of 439 Japanese subjects with atrophic gast...

BACKGROUND Antioxidant nutrients may reduce the risk of MS. In a recent case-control study, vitamin C intake was significantly inversely associated with MS risk among women. However, no prospective data are available. OBJECTIVE To examine prospectively the associations of intakes of carotenoids, vitamin C, and vitamin E with the risk of MS among women. METHODS The authors documented the occ...