A crossmatch test between patient and donor’s blood must be carried out before transfusion. However, not all crossmatched will transfused to the patient. This indicates inappropriate distribution of products, wastage, inaccessibility for emergency patients, increased costs, workload staff. Crossmatch Transfusion Ratio (C/T Ratio) is used as an indicator determine efficiency use can serve a guid...

Abstract Background and Aims AKI anemia independently worsen the prognosis of hospitalized patients, but their association adverse effects have been slightly studied. We aimed to investigate effect transfusions during hospitalization on hard renal clinical outcomes patients with AKI. In addition, we tested influence number mortality between pure (pAKI) AKI-on-CKD (AoCKD) patients. Method Retros...

BACKGROUND This study investigated the hypothesis that storage age of transfused red blood cells (RBCs) is associated with adverse outcome after cardiac surgery, and examined association between volume of RBC transfusions and outcome after cardiac surgery. METHODS Adult patients undergoing first time elective/urgent cardiac surgery who had received RBC transfusion perioperatively were include...

Objectives: Accurately identifying the Antigens (Ags) on recipient red blood cells (RBCs) is critical in prevention of RBC alloimmunization in chronically transfused patients. The goal of this study was to compare RBC molecular genotyping to serological phenotyping in those patients. Methods: Serological phenotyping and molecular genotyping methods were used to study blood samples from 18 healt...

The purpose of this study was to retrospectively evaluate the efficacy a tranexamic acid (TXA) perioperative protocol for primary hip- and knee arthroplasty, in terms allogenic blood transfusion rates. A retrospective cohort conducted included all hip arthroplasty procedures period 2014-2019. Patients who underwent surgery due trauma or revision were excluded. total amount 5205 patients eligibl...

Despite the general view that patients with sickle-cell disease (SCD) have iron overload, there are reports of iron deficiency in a proportion of these patients. We studied Yemeni patients aged 1-30 years with homozygous SCD to determine their iron status using a set of 4 criteria (low serum iron, low transferrin saturation, high total iron binding capacity and low mean corpuscular volume for a...

Patients with Glanzmann thrombasthenia (GT) may form isoantibodies which induce refractoriness or inhibition of function of transfused platelets. We monitored the survival and function of transfused platelets by flow cytometry and thrombelastography in a patient with GT. Gating on CD42a+ allowed identification of even a few transfused platelets. Only by gating on these CD41+ CD42a+ cells were w...

The purpose of pretransfusion compatibility testing is to prevent immune mediated hemolytic transfusion reactions. Our study aimed to evaluate the gel test for detection of clinically significant antibodies in repeatedly transfused patients. We investigated 200 thalassemic patients in whom, blood group, Rh-D, Rh phenotype determination, antibody screening and identification were done using an I...

Bone marrow transplantation (BMT) is now an option for some patients with sickle cell disease (SCD). Many SCD patients are multiply transfused with red blood cells (RBCs), and may be immunized to alloantigens other than erythrocyte antigens. Because platelet refractoriness is a significant complication during BMT, we wished to determine the prevalence of alloimmunization to platelets in transfu...