Transfusion of blood and blood preparations is indispensible in modern medicine, and the processes of delivering a transfusion to a patient provide additional opportunity for risk, despite the remarkable progress. A spectrum of blood-borne infectious agents is transmitted through transfusion of infected blood donated by apparently healthy and asymptomatic blood donors. The diversity of infectio...

In general, the risk of transfusion-transmitted infections has been greatly reduced today. However, blood-borne bacterial and parasitic infections and emerging infections transmitted through transfusion are an area of increasing concern. Implementation of stringent donor eligibility criteria, improved donor screening and more sophisticated as well as sensitive methods of antibody, antigen and v...

BACKGROUND GB virus C (GBV-C) infection is transmitted by blood exposure and associated with lower human immunodeficiency virus (HIV) load and slower HIV disease progression. Few studies describe predictors of acute GBV-C infection following transfusion in HIV-infected patients. METHODS We used a limited-access database from the National Heart Lung and Blood Institute's Viral Activation Trans...

Blood transfusion has a well-documented clinical significance in several medical scenarios for instance severe anemia, massive blood loss caused by trauma, and major surgeries. Nevertheless, been associated with post-transfusion complications, such as mismatch reactions, transfusion-transmitted infections (TTIs).

background: hepatitis a virus (hav) is a single strand and non-enveloped rna virus. it is usually transmitted by the fe­cal-oral and the blood transfusion routes and causes the hepatitis a disease. clinically, the hepatitis a is usually mild, par­ticularly in children, in whom it is frequently subclinical. the disease is more serious and prolonged in adults. the objective of this study was to f...

conclusions the analysis indicates that the hev isolated from blood donors in the southwest of iran belongs to genotype 1. however, more samples from other geographic regions of iran are needed to confirm these findings. because transmission of hev by administration of blood or blood components is likely to occur, it may be sensible to screen donor blood for hev to eliminate transfusion-transmi...