BACKGROUND Our aim was to evaluate the efficacy and toxicity of chemoradiotherapy (CRT) with transoral debulking microsurgery for T2N0 glottic cancer. METHODS Thirty patients with T2N0 glottic cancer treated with concurrent hyperfractionated radiotherapy (RT) and carboplatin were retrospectively analyzed. Median total dose of RT was 72 Gy. Nineteen of 30 patients also received transoral debul...

OBJECTIVES To determine the optimal approach for nasopharyngeal culture and to establish which approach children tolerate best. DESIGN Cross-sectional study. SETTING A pediatric otolaryngology department of a Dutch tertiary care hospital. PATIENTS A cohort of 42 children with chronic suppurative otitis media. INTERVENTION Paired nasopharyngeal samples were collected transorally and tran...

Recent advances now permit resection of many pharyngeal tumors through the open mouth, an approach that can greatly reduce the morbidity of surgical exposure. These transoral techniques are being rapidly adopted by the surgical community and hold considerable promise. On November 6-7, 2011, the National Cancer Institute sponsored a Clinical Trials Planning Meeting to address how to further inve...

OBJECTIVE To assess the application and safety of transoral robotic surgery in the pediatric airway. DESIGN An institutional review board-approved study. Experimental laryngeal surgery was performed on 4 pediatric cadaver larynxes as controls. Application of robotic equipment for laryngeal surgery was attempted on 5 patients. SETTING Tertiary care pediatric medical center. PATIENTS Five p...

BACKGROUND Transoral robotic-assisted oncologic surgery of the head and neck offers promising functional results. Nonetheless, the efficacy of oncologic surgery remains critically dependent on obtaining negative margins. We aimed to integrate a miniaturized high-resolution fiber-optic microendoscope (HRME), which provides real-time histological assessment, with the da Vinci robotic system (Intu...

The introduction of transoral endoscopic surgery has initiated a fundamental change in the treatment of head and neck cancer. The endoscopic approach minimizes the intraoperative trauma. Due to the lower burden for the patient and the savings potential these methods have gained wide acceptance. These transoral accesses routes allow experienced surgeons to reduce the morbidity of surgical resect...

BACKGROUND Modalities of surgical treatment of early glottic carcinoma include transoral laser microresection and external partial surgery. METHODS This is a retrospective analysis of 119 glottic carcinomas treated by external partial surgery (57 pT1a, 1 pT1b, 10 pT2) or transoral laser microresection (46 pT1a, 4 pT1b, 1 pT2) with special regard to initial anterior commissure involvement. R...

BACKGROUND Transoral laser microsurgery (TLM) is a mature approach to supraglottic cancer, while transoral robotic surgery (TORS) is emerging. The present study compared these approaches. METHODS The first 10 patients (2002-2005) given TLM were compared with the first 10 (2007-2011) given TORS for cT1-3 cN0-cN2c supraglottic cancer. RESULTS A feeding tube was used in four TLM and seven TORS...

INTRODUCTION Introduced a century ago by Bruening as a transoral procedure under general anesthesia, injection laryngoplasty is the oldest surgical management technique for vocal fold insufficiency. In 1985, Ward et al. introduced the office-based transcutaneous approach for vocal fold injection augmentation. They described the technique for Teflon injection under local anesthesia using the cri...

BACKGROUND Amidst a rising incidence of p16-positive (p16+) oropharyngeal cancer, a significant number of cases present as regionally metastatic disease with an "unknown" primary. Preliminary data support transoral surgery as an effective method of primary detection/treatment. METHODS An observational cohort study of 65 p16+ unknown primary patients treated with transoral surgery and neck dis...