Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation with Cyclosporin A (CsA) substantially enhanced the periosteal bone formation rates to levels observed in young animals. We therefore speculated that...

The objective of this study was to examine the effects of cyclic compressive loading on chondrogenic differentiation of rabbit bone-marrow mesenchymal stem cells (BM-MSCs) in agarose cultures. Rabbit BM-MSCs were obtained from the tibias and femurs of New Zealand white rabbits. After the chondrogenic potential of BM-MSCs was verified by pellet cultures, cell-agarose constructs were made by susp...

In this study, dynamic bearing capacity of adjacent shallow strip foundations located on sandy soil was examined using a numerical finite difference modeling, FLAC. The behavioral interference of shallow strip foundations under different conditions was investigated. The effect of soil strength parameters, geometric characteristics of shallow foundations and cyclic loads at different distance ra...

In this paper we describe new parallel cyclic wavefront algo rithms for solving the semide nite discrete time Lyapunov equation for the Cholesky factor using Hammarling s method by the message passing para digm These algorithms are based on previous cyclic and modi ed cyclic algorithms designed for the parallel solution of triangular linear systems The experimental results obtained on an SGI Po...

OBJECTIVE To investigate the biosynthetic response of elderly human femoral head articular cartilage to mechanical stimulation in vitro and its variation with site. METHOD Full-depth cartilage biopsies of articular cartilage were removed from defined sites on 10 femoral heads from patients aged 68-95 years. Cartilage explants were subjected to either static or cyclic (2s on/2s off) loading in...

The assessment of response of composite seismic force resisting systems requires accurate nonlinear formulations for the composite members. In this work, reporting the first phase of a NEES project, a three-dimensional distributed plasticity formulation is presented for both circular and rectangular composite concrete-filled steel tubes (CFTs) that includes new constitutive models for the concr...

In contrast to nailed connections, little research has been done on bolted connections using a reversed cyclic loading scheme, although cyclic loading provides important information about energy absorption and damping properties, which is essential when analyzing seismic performance. Dowrick (1986) noted that the hysteretic characteristics for the primary connection of a subassembly govern its ...

The safety of lifelines, as the most important urban facilities, under different conditions highly depends on the safe design and performance of these buried structures. This cannot be achieved unless their actual behaviors are well understood and considered at the designing stage. A new physical model was developed in Amirkabir University of Technology to study the behavior of buried pipes und...

OBJECTIVES Microbial leakage through the implant-abutment (I-A) interface results in bacterial colonization in two-piece implants. The aim of this study was to compare microleakage rates in three types of Replace abutments namely Snappy, GoldAdapt, and customized ceramic using radiotracing. MATERIALS AND METHODS Three groups, one for each abutment type, of five implants and one positive and o...