Methods of ;wet preparation', stained films, and culture were used to detect trichomonads in vaginal exudate and the results of these methods are compared. A method using a wet preparation and Oxoid no. 2 Trichomonas medium is reliable for routine use.

Over a period of 10 years very satisfactory results have been obtained in the treatment of trichomoniasis in women with a 7-day course of 'Flagyl' at a dosage of 200 mg. three times a day, without any concomitant local therapy (Rodin, King, Nicol, and Barrow 1960). In view of the known unreliability of patients in following any dosage schedule, it was felt that a simpler and shorter regimen wou...

A comparison is made between oral ornidazole in a single 1-5 g dose and tinidazole given in a 2 g dose using a double-blind technique. All the 45 women with Trichomonas vaginalis infection who were treated with ornidazole were cured. In the tinidazole-treated group 41 out of 43 women had negative cultures after treatment. Tolerance was good in both groups.

Human genital trichomoniasis has. received a good deal of Attention in recent years, but there are still many aspects of this disease which need fuller investigation. This paper, based on work carried out at the London Hospital during the past 2i years, is offered as an aid in elucidating certain of the more important of these problems-namely, the incidence, mechanism of infection, cause of rel...

Broth culture of Trichomonas vaginalis is considered the "gold standard" for the diagnosis of trichomoniasis. Two studies were carried out to evaluate modified Columbia agar (MCA) for the isolation of T. vaginalis from clinical samples. Study I compared isolation on MCA to that on liquid medium with 889 vaginal samples. Out of 63 samples positive for T. vaginalis (7.1% of total), MCA identified...

The local treatment of trichomonal vaginitis usually results in cure, but there are the following exceptions: (1) Some cases are resistant to treatment from the start. (2) Local treatment of the vagina can have no effect upon infection of the urethra, from which the vagina is re-infected. (3) In trichomonal urethritis in the male, local methods of treatment up to now have been of little effect,...

Despite the declining rate of sexually transmitted diseases in developed countries, trichomoniasis is still one of the most common venereal infections. While diagnosis of this condition is commonly based on the microscopic wet-mount method, culture remains the most accurate single procedure for detecting the presence of Trichomonas vaginalis in clinical samples. In the present study, the effica...

There is some difference of opinion regarding the incidence of vaginal thrush following the treatment of trichomonal vaginitis with the new oral trichomonicide, metronidazole ("Flagyl"). Rees (1960) and Rodin, King, Nicol, and Barrow (1960) concluded that metronidazole neither encouraged nor inhibited the growth of the fungus concerned. Watt and Jennison (1960) found coincident monilial infecti...

Feminists have been heard to say that the late entry of women into the ranks of the medical profession has meant that, left to the tender mercies of mere men, the ills to which female flesh is heir have not been given the attention which they deserved. Our knowledge, for example, of the cause and prevention of mammary carcinoma seems to have made little advance since Ramazzini reported in 1713 ...