introduction: breast cancers are divided into at least 4 sub types on the basis of gene expression profiles and expression of receptors as measured by ihc (immunohistochemical). triple negative breast cancer (tnbc) is more chemosensitive yet, it is much harder to detect than other sub types. at present lack of highly effective therapeutic targets for tnbc, leaves standard chemotherapy, as the o...

Purpose: To conduct an exploratory analysis of the relationship between gene expression and recurrence in patients with operable triple-negative breast cancer (TNBC) treated with adjuvant doxorubicin-contain-

Breast cancer is a big challenge for universal public health and has made as nuisance for every people who suffered from this disease. It is the second most common cause of cancer-related deaths in women worldwide. Triple-negative breast cancer (TNBC) is an advanced multi-drug resistance (MDR) breast cancer which affect majority of women worldwide Bakrania et al. [1]. TNBC is distinct by the la...

Breast cancer is a big challenge for universal public health and has made as nuisance for every people who suffered from this disease. It is the second most common cause of cancer-related deaths in women worldwide. Triple-negative breast cancer (TNBC) is an advanced multi-drug resistance (MDR) breast cancer which affect majority of women worldwide Bakrania et al. [1]. TNBC is distinct by the la...

Breast cancer is a big challenge for universal public health and has made as nuisance for every people who suffered from this disease. It is the second most common cause of cancer-related deaths in women worldwide. Triple-negative breast cancer (TNBC) is an advanced multi-drug resistance (MDR) breast cancer which affect majority of women worldwide Bakrania et al. [1]. TNBC is distinct by the la...

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (Her2/neu). TNBC has worse clinical outcomes than other breast cancer subtypes. However, the key molecules and mechanisms of TNBC migration remain unclear. In this study, we compared two normalized microa...

Triple negative breast cancer (TNBC) is a that aggressive with short survival rate. In comparison to other subtypes, TNBC tumors are bigger, more chemo resistant, highly proliferative, and usually abundant in stem immune cells. These modifications functionally dependent on high-quality endoplasmic reticulum mitochondrial pool. Endoplasmic health monitored enhanced regular basis via dynamics. Th...

Adenoid cystic carcinoma of the breast (breast-ACC) is a rare and indolent tumor with a good prognosis despite its triple-negative status. However, we observed different outcomes in the present study. Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, we enrolled a total of 89,937 eligible patients with an estimated 86 breast-ACC cases and 89,851 invasive ductal carcinom...

The repertoire of antigens associated with the development of an autoimmune response in breast cancer has relevance to detection and treatment strategies. We have investigated the occurrence of autoantibodies associated with the development of triple-negative breast cancer (TNBC) in the before diagnosis setting and in samples collected at the time of diagnosis of TNBC. Lysate arrays containing ...

Patients with triple-negative breast cancer (TNBC) have a high incidence of early relapse and metastasis; however, the molecular basis for recurrence in these individuals remains poorly understood. Here, we demonstrate that RASAL2, which encodes a RAS-GTPase-activating protein (RAS-GAP), is a functional target of anti-invasive microRNA-203 and is overexpressed in a subset of triple-negative or ...