Abstract During 2019 a series of food poisoning events and deaths occurred in Uganda due to an unknown causative agent. In response the World Food Programme (WFP) initiated investigations into incidents which included contacting expert laboratories analyse main suspect product known as Super Cereal. The used broad gamut their testing capabilities determine cause incidents. This targeted non-tar...

background: plants infection with microorganisms as well as physical factors such as osmotic stresses especially drought stress induced particular secondary metabolite production. objective: plant root and shoot hyoscyamine (hyo) and scopolamine (sco) variations were investigated under three water deficit stress (wds) levels as 30 (w1), 60 (w2) and 90 % (w3) water depletion of field capacity an...

Secondary metabolites of Solanaceae plants, sharing tropane skeleton as a common structural feature, are sharply divided into two classes: tropine and ecgonine derivatives. The first group, represented by well known alkaloids: atropine and scopolamine, which are considered to be model anticholinergic drugs, continues to provide inspiration in the search for more selective muscarinic receptor an...

Corresponding author: Ryszard ŁAŹNY Ph.D., D.Sc., Professor, e-mail: [email protected] Introduction Stereochemical elucidation of bioactive natural products is of paramount importance for understanding their chemical and biological properties. Tropane alkaloids are a well-known and important class of natural products because of their pharmacological activities as anticholinergic agents. They are...

Plant tissue culture techniques were used to study the effect of NaCl on tropane alkaloids accumulation and proline content of both Datura metel and Datura stramonium. Callus cultures were established for both Datura species. However, MS medium supplemented with 1mg/l of both BA and NAA was the best for callus production in D. metel, while MS supplemented wit...

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Due to its tropical location, chains of mountains, inter-Andean valleys, Amazon basin area, eastern plains and shores on both the Atlantic and Pacific Oceans, Colombia has many ecosystems and the second largest plant biodiversity in the world. Many plant species, both native and naturalized, are currently recognized as toxic for both animals and humans, and some of them are known to cause their...

Tropane alkaloids have received much attention because many of them reveal remarkable biological activity (1-5). Compounds with tropinone structure or related 8-azabicyclo[3.2.1]octane skeletons have attracted considerable attention in medicinal chemistry because of their influence on neurotransmitters. They are of interest as analogues of cocaine and other physiologically active compounds and ...