This report illustrates an adult patient presenting with tumefactive acute disseminated encephalomyelitis complicating human swine influenza. Its presentation, diagnosis, investigation findings, course, and response to treatment are discussed herein.

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis.  Clinical P...

tumefactive fibroinflammatory lesions (tfls) are rare idiopathic benign fibrosclerosing lesions that clinically simulate a malignancy. tfls are seen more frequently in males between 10 and 74 years of age. the usual site of involvement is the head and neck region, but rarely the extremities may be involved. coexisting fibrosclerotic processes have been reported including retroperitoneal fibrosi...

W e present a case of a large solitary demyelinating plaque in the brain masquerading as tumour. A 34 year old healthy woman presented with sudden onset of left hemiparesis. Subsequent MRI of the brain showed a single large 2.5 cm right sided enhancing lesion within the white matter of the parietal lobe (fig 1). The lesion appeared to originate from the corpus callosum. Diffusion weighted and g...

A previously healthy 31-year-old woman presented with a 2-week history of progressive left hemiparesis. MRI (figure) demonstrated a 3 cm enhancing mass in the right posterior frontal white matter with several smaller lesions in the white matter of the contralateral hemisphere and brainstem (figure, D). A stereotactic biopsy of the large lesion was performed to establish the diagnosis. This show...