Autoimmune diseases develop in selected normal mouse strains when thymectomy (Tx) is performed at 3 days of age (d3-Tx). Insufficient T cell regulation after Tx may result from a defect in regulatory T (Treg) cells or from an augmented effector T (Teff) cell number/pathogenicity. We have previously shown that Tx at 3 wk (wk3-Tx), the age of massive islet Ag release, accelerates diabetes onset. ...

OBJECTIVE To investigate the significance of tendon xanthomas (TX) in heterozygous subjects with familial hypercholesterolemia (hFH). METHODS AND RESULTS 951 men and women with genetic diagnosis of hFH were studied, of whom 278 (29.2%) presented TX. TX frequency increased with age from 6.9% in subjects 20 to 30 years to 38.3% at 51 to 60 years, with a decrease in those older than 60 years. To...

1 Silicon Laboratories, Corporate Headquarters, 7000 West William Cannon Drive, Austin, TX 78735, USA 2Schlumberger Sugar Land Product Center, 110 Schlumberger Drive, Sugar Land, TX 77478, USA 3Schlumberger Austin Systems Center, 8311 N FM 620 Road, Austin, TX 78726, USA 4TICOM Geomatics, 9130 Jollyville Road, Austin, TX 78759, USA 5Department of Electrical and Computer Engineering, The Univers...

Soil-washing is a potential technology for the disposal of soil contaminated by e-waste; however, produced soil-washing effluent will contain polybrominated diphenyl ethers (PBDEs) and large number surfactants, which are harmful to environment, so treatment PBDEs recycling surfactants key application technology. In this study, coconut shell granular-activated carbon (GAC) was applied remove fro...

In an Frequency-Division Duplexing (FDD) transceiver, a high power transmitted signal can leak into the RX chain due to limited isolation of a duplexer. Such signal is known as TX leakage and can seriously affect the performance of the receiver. A transmitter leakage canceller structure is proposed in this paper in order to improve isolation between the transmitter and receiver. The simulations...

BACKGROUND Current organ allocation algorithms direct hearts to the sickest recipients to mitigate death while waiting. This may result in lower post-transplant (Tx) survival for high-risk candidates mandating close examination to determine the appropriateness of different technologies as a bridge to Tx. METHODS AND RESULTS We analyzed all patients (<18 years old) from the Pediatric Heart Tra...

Triton X-100 (TX-100), a useful non-ionic surfactant, reduced the methicillin resistance in Staphylococcus aureus significantly. Many S. aureus proteins were expressed in the presence of TX-100. SarA, one of the TX-100-induced proteins, acts as a global virulence regulator in S. aureus. To understand the effects of TX-100 on the structure, and function of SarA, a recombinant S. aureus SarA (rSa...

This paper studies a general p-contractive condition of self-mapping T on X, where X ,d is either metric space or dislocated space, which combines the contribution to upper-bound dTx , Ty, x and y are arbitrary elements in weighted combination distances dx,y dx,Tx,dy,Ty,dx,Ty,dy,Tx, dx,Tx−dy,Ty dx,Ty−dy,Tx. The asymptotic regularity convergence Cauchy sequences unique fixed point also discussed...

a Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA b Department of Phamarcology & Toxicology, University of Texas Medical Branch, Galveston, TX, USA c Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA d Sealy Center for Vaccine Development, University of Texas Medical Branch, G...