نتایج جستجو برای: unfolded protein response
تعداد نتایج: 2053215 فیلتر نتایج به سال:
Journal:
Iranian Biomedical Journal
2016
Ali Bazi,
Mehran Gholamin,
Mohammad Reza Keramati,
Background: Recently, it has been revealed that tyrosine kinase inhibitors (TKIs) act through inducing both oxidative and endoplasmic reticulum (ER) stress in chronic myeloid leukemia cells. However, ER stress signaling triggers both apoptotic and survival processes within cells. Nevertheless, mechanisms by which TKIs avoid the pro-survival effects are not clear. The aim of this study was to ev...
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