Graft failure is a major complication after unrelated cord blood transplantation. Presence of HLA-antibodies before cord blood transplantation may impact graft failure. To analyze the effect of anti-HLA antibodies on unrelated cord blood transplantation outcomes, we analyzed 294 unrelated cord blood transplant recipients after reduced intensity conditioning regimen. The majority of the patients...

Kidney donation and transplantation in Iran has passed a long history from the first kidney transplant in 1967, starting living related transplant in 1988 to 1989, adopting state-regulated livingunrelated donor kidney transplant program in 1988, religious approval from the Supreme Religious Leader for brain death in 1989, legislation law for cadaveric transplant in 2000, and increased number of...

This retrospective analysis of cytomegalovirus (CMV)-seropositive adult transplant recipients showed that CMV antigenemia occurred after transplantation in 10/10 (100%) recipients of unrelated cord blood, 17/39 (43%) recipients of a related matched donor graft, 16/23 (79%) recipients of an unrelated matched donor graft, and 8/12 (67%) recipients of a mismatched related donor graft. These result...

BACKGROUND/AIMS Kidney transplantations at our center rely mainly on living donors. The purpose of this study was to suggest future donor supply directions by reviewing changing trends in donor type. METHODS During the past 40 years, 1,690 kidney transplantations were performed at our center. We divided the follow-up period into four decades and the donor population into three groups: living ...

Kidney donor risk index Kidney transplantation, Kidney Donor Risk Index (KDRI), Kidney Donor Profile Index (KDPI)

BACKGROUND A growing body of evidence demonstrated an immune etiology as well as nonimmune mechanisms for episodes of clinical acute rejection and long-term allograft dysfunction. OBJECTIVE To investigate the correlation of IFN-γ-producing cells and TGF-β with incidence of clinical acute rejection in living-related and unrelated kidney allogarft recipients during the first post-transplant yea...

Renal transplantation represents the best available replacement treatment for patients with end stage renal disease patients than performing dialysis, and living donor transplantation has been shown to offer better graft survival than cadaver donor renal transplantation. It was demonstrated that kidneys from living, unrelated donors succeed as well as kidneys obtained from brothers and sisters ...

This study aimed to investigate the impact of grafting using thin upper pole artery ligation for living-donor adult kidney transplantation. Few reports have examined the safety of thin upper pole artery ligation.Between January 2008 and May 2015, 613 consecutive living-donor adult kidney transplantations were performed. We excluded 21 recipients who experienced graft loss due to factors that we...