objective(s): we aimed to study the effect of trimetazidine (tmz) on urethral wound repair. materials and methods: a total of 52 male rats were used; 8 groups were formed: 1-week and 3-week control (c1,c3), sham (s1, s3), oral (ot1, ot3), and intraurethral tmz (iut1, iut3) groups. serum and urine total antioxidant capacity (tac), total oxidant capacity (toc), and 8-hydroxy-deoxy-guanosine (8-oh...

PURPOSE The purpose of this study was to examine whether urethroplasty with a turnover flap, as an alternative method of distal hypospadias repair in adolescents, improves the outcome of surgery. MATERIALS AND METHODS Between January 2004 and December 2013, a total of 38 adolescents (aged 11-17 years) underwent distal hypospadias repair with either the tubularized incised plate (TIP) procedur...

PURPOSE To present the results of a two-stage technique used for the treatment of proximal hypospadias with severe curvature. MATERIALS AND METHODS The medical records of children with proximal hypospadias and severe curvature were retrospectively analyzed. A 2-stage procedure was performed in 30 children. In the first stage, the release of chordee was performed, and a well-vascularized prepu...

Purpose: Female epispadias is a rare anomaly. According to the literature it is usually treated with staged procedures, including bladder neck reconstruction, to achieve continence. We developed a 1-stage surgical technique that offers the possibility of achieving continence and a cosmetically normal appearance of the vulva. Materials and Methods: We treated 4 patients 4 months to 8 years old. ...

A 4-day-old male newborn, weighing 2.5 Kg, delivered vaginally at 38 weeks presented with malformed external genitalia and a reddish swelling over the lower part of the abdomen and the absent anal opening with a small perineal opening. Pregnancy was uneventful. Maternal serologies for HbsAg, HCV, HIV, Toxoplasma, and Rubella were planned but due to financial reason not done. Physical examinatio...

PURPOSE Tubularized Incised Plate (TIP) urethroplasty is a technique for urethral reconstruction of hypospadias although there are some controversies for its use in recurrent cases. The aim of this study was to review the results of TIP technique in various studies and the usage of different flaps for covering the repair site. MATERIAL AND METHODS Extensive Search was performed for articles p...

INTRODUCTION Since its first description in 1994, tubularized incised plate (TIP) technique has become the most commonly performed hypospadias procedure and involves incision of the urethral plate with subsequent tubularization. Glans wings are then developed to cover the neourethra, thereby creating a cosmetically appealing repair. In some distal hypospadias cases, mobilization and approximati...

BACKGROUND Repair of penile urethral strictures is a challenging problem for which different techniques have been suggested. OBJECTIVE To describe a new surgical technique for one-stage penile urethroplasty using an oral graft and glue, and to assess its safety and efficacy. DESIGN, SETTING, AND PARTICIPANTS A retrospective review of medical records for patients who underwent one-stage peni...