histamine h3 receptor subtype has been the target of several recent drug development programs. quantitative structure-activity relationship (qsar) methods are used to predict the pharmaceutically relevant properties of drug candidates whenever it is applicable. the aim of this study was to compare the predictive powers of three different qsar techniques, namely, multiple linear regression (mlr)...

purpose: to determine peripapillary retinal nerve fiber layer (rnfl) thickness by three-dimensional optical coherence tomography (3d-oct) in a normal iranian population and to evaluate the concordance of these measurements with those obtained by the second generation of optical coherence tomography (oct ii). methods: in a cross-sectional observational study, 96 normal iranian subjects 20-53 yea...

the system dynamics technique is an object-oriented approach that studies and manages complex feedback systems. its merits include the friendly and easy development and improvement of a model. it is also used as a decision tool for engineering problems. in this paper, the system dynamics technique was used to simulate the performance of a subsurface drainage system in an unsteady state. the mod...

in this research, the spatial distribution of electrical conductivity and ph of springs, ghanats and the base flow concentration places on the streams of central and south-west and central parts of the hamedan-bahar plain were evaluated. using different geostatistical methods such as kriging, minimum curvature, inverse distance, natural neighbor, local polynomial and radial basis functions, 108...

A retrospective evaluation of attitudinal, behavioural and knowledge change among diverse stakeholder groups was conducted in Limpopo Province of South Africa to assess the effectiveness of a series of values clarification (VC) interventions. Telephone and face-to-face interview (193) results revealed that over two-thirds (70.2%) reported behavioural changes and 93.2% reported increased compass...

Learning about statistics is a lot like learning about science: the learning is more meaningful if you can actively explore. This series in Advances in Physiology Education provides an opportunity to do just that: we will investigate basic concepts in statistics using the free software package R. Because this series uses R solely as a vehicle with which to explore basic concepts in statistics, ...