OBJECTIVE To investigate the risk of uterine fibroids and other reproductive risk factors in women with hereditary leiomyomatosis and renal cell cancer (HLRCC). DESIGN Case-control study. SETTING National Institutes of Health, Rockville, Maryland. Patients A family-based case-control study was conducted between July 1, 2004, and June 30, 2006, including 105 women from families with HLRCC as...

CASE HISTORY A 35-year-old woman (gravida 3, para 0030) presented with complaints of abdominal discomfort and distension, dysmenorrhea, and menorrhagia. Physical examination revealed a pelvic mass comparable to 38 weeks’ gestation, thought to consist of uterine fibroids. The tumors displaced the anatomic position of the cervix, making it impossible to obtain an endometrial biopsy sample. Comput...

OBJECTIVE The aim of the study was to investigate the prevalence of endometrial polyps in patients with uterine fibroids and associated factors of coexistence of these two pathologies. MATERIALS AND METHODS The medical records of 772 patients who underwent hysterectomy because of uterine fibroids were retrospectively reviewed. Patients were divided into two groups according to the presence of...

OBJECTIVE To investigate the impact of fibroids on the blood flow of the uterine and subendometrial arteries and in vitro fertilization (IVF) outcomes. METHODS In this study, we analyzed 86 IVF/intracytoplasmic sperm injection (ICSI) cycles in which a gonadotropin-releasing hormone antagonist protocol was used for controlled ovarian stimulation between January 2008 and March 2009. The subject...

BACKGROUND To assess the impact of intramural fibroids on the intracytoplasmic sperm injection-embryo transfer (ICSI-ET) cycle outcome, when there is no compression of the endometrial cavity. METHODS In this retrospective, matched control study, the ICSI-ET outcome of sixty-two patients (Group I) with intramural fibroid (mean diameter <7 cm) and normal endometrial cavity demonstrated by offic...

difficulties except those occasioned by the size of the tumour. The incision to deliver the tumour extended, from the pubes to the umbilicus and the weight and size of the tumour hindered considerably the subsequent steps of the operation. The broad ligaments which were greatly hypertrophied contained a large number of immense thin walled veins, some the size of the little finger, the ligation ...

OBJECTIVE To present the rationale, design, and methodology of the Fibroid Interventions: Reducing Symptoms Today and Tomorrow (FIRSTT) study. DESIGN Randomized clinical trial. SETTING Two academic medical centers. PATIENT(S) Premenopausal women with symptomatic uterine fibroids. INTERVENTION(S) Participants are randomized to two U.S. Food and Drug Administration-approved minimally inva...

PURPOSE To estimate the prevalence of women diagnosed with uterine fibroids and the associated symptom burden in the US. PATIENTS AND METHODS Responses of women aged 18-54 years, who completed an online survey, were analyzed. Data were weighted based on age, education, race, geographic region, income, and propensity score to derive national estimates of the prevalence of women diagnosed with ...

Uterine fibroid or fibromyoma is a very common benign human tumor and the most frequent tumor in the woman’s reproductive system. Uterine fibroids affect millions of women across the world and they are still the most commonly surgically treated. In Romania too, uterine fibroid is the most common reason for hysterectomy, about 60% of cases have this diagnosis preoperatively established. Uterine ...

We decided to evaluate the efficacy and complications of uterine artery embolization (UAE) in patients with symptomatic uterine fibroids. Sixty-five premenopausal patients, without considering the fibroids size and its location, were treated by bilateral UAE. At baseline and after 3, 6, and 12 months MRI was obtained to determine the uterine length and fibroid diameter. In addition, symptoms of...