OBJECTIVES To evaluate the effect of Carbopol gel formulations containing pilocarpine on the morphology and morphometry of the vaginal epithelium of castrated rats. METHODS Thirty-one female Wistar-Hannover rats were randomly divided into four groups: the control Groups I (n=7, rats in persistent estrus; positive controls) and II (n=7, castrated rats, negative controls) and the experimental G...

OBJECTIVE In this study, we aimed at evaluation of the efficacy of Hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women. MATERIALS AND METHODS We searched MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials (RCT) to explore trials that assessed the effectiveness of H. perforatum and flaxseed on hot flash, vagina...

Spontaneous evisceration through the vagina was first described in 1907 by McGregor. To date, only eighty-five cases of transvaginal small bowel evisceration have been documented worldwide. The primary risk groups for spontaneous vaginal evisceration include postmenopausal women, vaginal surgery cases, multiparae, and women of older age. In postmenopausal woman, transvaginal evisceration is fre...

Vulvovaginal atrophy (VVA) and dryness are common symptoms of the decline in endogenous production of estrogen at menopause and often result in dyspareunia. Yet while 10% to 40% of women experience discomfort due to VVA, it is estimated that only 25% seek medical help. The main goals of treatment for vaginal atrophy are to improve symptoms and to restore vaginal and vulvar anatomic changes. Tre...

Abstract This interventional clinical study aimed to assess the efficacy of oral intake a food supplement containing 200 mg sodium hyaluronate (SH) as adjuvant radiofrequency (RF) and radioporation (RP) treatment in menopausal women suffering vulvovaginal atrophy. The was carried out thirty patients with diagnosis atrophy who underwent treatments. Half test subjects received supplement. primary...