BACKGROUND Factors that influence shedding of HIV-1 infected cells in cervical and vaginal secretions may be important determinants of sexual and vertical transmission of the virus. We investigated whether hormonal contraceptive use, vitamin A deficiency, and other variables were risk factors for cervical and vaginal shedding of HIV-infected cells. METHODS Between December, 1994, and April, 1...

Address for Correspondence: Cihat Ünlü, Women’s Health Clinic, Abdi Ipekci Caddesi 2/7, 34357 Nişantaşı, İstanbul, Turkey Phone: +90 212 241 45 45 Fax: +90 212 241 44 08 e.mail: [email protected] ©Copyright 2011 by the Turkish-German Gynecological Education and Research Foundation Available online at www.jtgga.org doi:10.5152/jtgga.2011.57 To maintain a healthy vaginal ecosystem or to restore an...

Background: Cancer of the cervix is commonest cancer in women seen at Diseases Hospital in Zambia and Pelvic Radiotherapy main treatment modality used on cervical cancer patients. to pelvis has a potential causes vaginal stenosis but can be prevented by regular sexual intercourse or use vaginal dilators as recommended by organizations. Despite well-established benefits vaginal dilators, ...

Gestational choriocarcinoma ended with a successful parturition is extremely rare, especially in cases where multiple metastases occurred.A 29-year-old Chinese primigravida was admitted with vaginal bleeding at 32 gestational week, and diagnosed with gestational choriocarcinoma with vaginal, pulmonary, and cerebral metastasis after pathological, and imaging examination. At 33 gestational week, ...

OBJECTIVES To determine whether periodontal disease or bacterial vaginosis (BV) diagnosed before pregnancy increase the risk for adverse pregnancy outcome. METHODS We enrolled a total of 252 women who had discontinued contraception in order to become pregnant. The first 130 pregnant women were included in the analyses. RESULTS Multivariate analysis showed a strong association between period...

Nonspecific vaginitis (NSV), also named bacterial vaginosis, is one of the most common genital system diseases in women during their reproductive years. The specific pathogenic mechanism of NSV is not clear yet. Upon the balance alteration, large amount of reactive oxidant species (ROS) is generated and accumulated in the genital tract, and thus resulting in oxidative stress, which has been rep...

Nanopharmaceuticals have the potential to revolutionise medical treatment by permitting the design of more potent, less toxic "smart" therapeutics, ultimately leading to personalised medicine. This review summarises the challenges and potential uses of nanodelivery system for the topical drug therapy of vaginal diseases. The vaginal route of drug administration remains a challenge in the develo...

Vulvovaginal Candidiasis (VVC) represents a spectrum of disease. Although it is the second most common vaginal infection, VVC is a non notifiable disease and has been excluded from the ranks of sexually transmitted diseases. For many years patients with vaginal Candida were categorized into two groups: Asymptomatic carriers of Candida (colonization) and Symptomatic disease (Vaginal Candidiasis)...