the present study concerned with the development and characterization of metronidazole microcapsules prepared by thermal change method using different ratios (1:1, 1:2 and 1:4) of ethyl cellulose in order to select the best microcapsule formulation with a good encapsulation efficiency and drug release profile. the obtained microcapsules were discrete, spherical with free flowing properties and ...

Leiomyoma of the urethra is a rare clinical entity. We report an unusual presentation of this tumour, which led to a diagnostic and surgical dilemma. The patient was a 16year old female who presented with a labial mass which was palpable abdominally. Imaging methods and laparoscopy demonstrated a well defined soft tissue mass arising from the pelvis, without any obvious involvement of the urina...

Objective(s): The ability to measure cellular proliferation non-invasively in renal cell carcinoma may allow prediction of tumour aggressiveness and response to therapy. The aim of this study was to evaluate the uptake of 18Ffluorothymidine (FLT) PET in renal cell carcinoma (RCC), and to compare this to 18F-fluorodeoxyglucose (FDG), and to an immunohistochemical measure of cellular proliferatio...

Micropapillary variant of urothelial carcinoma (UC) of the bladder is an aggressive tumour, comprising 0.6-6% of all UC. It generally presents with high-grade and stage, and has been reported as having a worse prognosis when compared to traditional UC. We report the case of a 58-year-old man who presented with macroscopic haematuria. The patient was diagnosed with high-grade urothelial carcinom...

OBJECTIVES The aim of the study was to estimate acute and late complications of radiation therapy in primary invasive vaginal carcinoma (PIVC) patients. MATERIAL AND METHODS The analysis was performed for the group of 152 PIVC patients given radical radiotherapy in the Krakow Branch of Centre of Oncology during the 1967-2005 period. Twenty five (16.5%) patients in I stage with primary tumour ...

A woman in her mid-60s presented with a bulky mass on the anterior abdominal wall. She had a previous incidental diagnosis of endometrial adenocarcinoma FIGO stage IB following a vaginal hysterectomy. Physical exam and imaging revealed a well circumscribed bulging tumour at the umbilical region, measuring 10 × 9 × 9 cm, with overlying intact skin and subcutaneous tissue. Surgical resection was ...

the aim of the present study is to evaluate the effect of ethanolic extract of leaves of leptadenia reticulata leaves (lelr) against dalton’s ascitic lymphoma (dal) in swiss albino mice. dal cells were injected intraperitoneally (106 cells/mouse) to the mice. two days after cells injection the animals were treated with 200 mg/kg of lelr for 8 days. five-fluorouracil (20 mg/kg) was used as refer...

introduction urogenital atrophy is a common problem after menopause, and results from declining estradiol levels and may causes symptoms that can significantly affect quality of life. the aim of this study was to determine the effect of the vaginal suppository of vitamin e in the treatment of atrophic vaginities. materials and methods this randomized, double-blind controlled trail study was car...

Ovarian germ cell tumours are very rare and affect mainly young girls and women. Due to this, the conservation of reproductive potential is of great concern. One of the most remarkable advances in oncology is in the treatment of malignant ovarian germ cell tumours. Two histological groups are distinguished: dygerminomas, equivalent to testicular seminomas, and non-dysgerminomatous tumours. We r...

The diagnosis of villoglandular adenocarcinoma of cervix on cytological smears is often missed due to the relatively bland cytological features of this tumour. A 45-year-old female with an exophytic cervical growth had three cervical smears reported as unsatisfactory. A cervical biopsy followed by Wertheim's hysterectomy showed a villoglandular adenocarcinoma (VGA) of cervix. Vaginal recurrence...