insulin resistance syndrome, also referred to as the metabolic syndrome or syndrome x, refers to a constellation of common metabolic and cardiovascular disorders (e.g. obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia), which are all cardiovascular risk factors. insulin resistance can be induced by fructose-rich diet in rats. we investigated the effect of vanadyl sulfate (0.2 mg...

Two new tetradentate oxovanadium(IV) and iron(II) Schiff base complexes have been prepared by the interaction of vanadyl(IV) iron(III) acetylacetonate with ligand obtained from reaction ethylenediamine 5?-(N-methyl-N-phenylaminomethyl)-2?-hydroxyacetophenone in methanol. These characterized means different spectroscopic techniques such as UV–visible, FT-IR, mass spectrometry, elemental analysis...

To determine whether insulin resistance and hyperinsulinemia are causally related to fructose-induced hypertension, we used vanadyl sulfate, a drug that improves insulin sensitivity in rats. Chronic oral vanadyl treatment was initiated in 6-week-old male Sprague-Dawley rats. One week after vanadyl was started, rats were fed either normal rat chow or a fructose-enriched diet. Plasma glucose and ...

BACKGROUND The National Toxicology Program (NTP) performed short-term toxicity studies of tetra- and pentavalent vanadium compounds, vanadyl sulfate and sodium metavanadate, respectively. Due to widespread human exposure and a lack of chronic toxicity data, there is concern for human health following oral exposure to soluble vanadium compounds. OBJECTIVES To compare the potency and toxicologi...