Objective: To investigate the incidence of vascular injury in lumbar spine surgery and determine the strategy for its diagnosis and treatment. Methodology: We retrospectively reviewed 1159 patients in our institution treated with lumbar spine surgery from September 2003 to November 2009. Primary outcomes measured included intraoperative vascular complications, operative blood loss and operative...

I n this paper I introduce some new developments in the study of lung vascular injury and revisit some older approaches that need a fresh look. Lung vascular injury is becoming more and more fascinating as findings and techniques in other fields are adapted to lung vessels. Most topics of the Aspen Conference related to lung vascular injury; I tried to avoid duplication and concentrated on a fe...

Injury to the major peripheral arteries or veins is often lifethreatening but invariably poses a threat to the viability of the affected limb. Historically, because of rapid blood loss, injury to major vessels was often quickly fatal in the field. Most patients who survived to reach a hospital had relatively minor vascular injuries. However, with the advent of modern emergency medical services ...

Blood vessel cells express the 2 known estrogen receptors, and (ER , ER ), which are thought to mediate estrogen inhibition of vascular injury and atherosclerosis, but the relative role of ER and ER in these events is controversial. Estrogen inhibits the vascular injury response to the same extent in ovariectomized female wild-type mice and in the original single gene knockout mice for ER (ER K...

Background Maintenance of vascular homeostasis depends on phenotypic switching of vascular smooth muscle cells (VSMCs) during development, vascular injury repair, and disease. In healthy blood vessels, VSMCs exhibit a differentiated, ‘contractile’ phenotype, but in diseased vascular tissue or after vascular injury, they de-differentiate into a ‘synthetic’ state, characterized by decreased smoot...

Aim: Vascular and cardiac injuries are rare cases compared to other traumas in terms of admission rates emergency services. emergencies secondary trauma among 1-2.5% all patients admitted the department. In addition, rate heart is around 1%. With this study, we will analyze interpret cardio-vascular injuries, which traumas, from a forensic-medical aspect.
 Material Method: This study retro...

Although morphological studies suggest that coronary vascular injury is a result of prolonged ischemia and subsequent reperfusion, whether functional coronary microvascular injury develops during brief in vivo ischemia is unclear. In other organs, permeability is a sensitive indicator of functional vascular injury. Therefore, a new double-indicator method of assessing vascular protein permeabil...

Vascular NAD(P)H oxidase-derived reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) have emerged as important molecules in the pathogenesis of atherosclerosis, hypertension, and diabetic vascular complications. Additionally, myeloperoxidase (MPO), a transcytosable heme protein that is derived from leukocytes, is also believed to play important roles in the above-mentioned inflammato...

BACKGROUND Contemporary war-related studies focus primarily on adults with few reporting the injuries sustained in local pediatric populations. The objective of this study is to characterize pediatric vascular trauma at US military hospitals in wartime Iraq and Afghanistan. METHODS Review of the Department of Defense Trauma Registry (DoDTR) (2002-2011) identified patients (1-17 years old) tre...

Normal pulmonary vascular development is the result of a complex interplay of growth factors, including vascular endothelial growth factor (VEGF) and the angiopoietins. Injury to the developing lung, whether due to hyperoxia or mechanical ventilation, results in disordered vascular development, ranging from an apparent arrest of microvascular development in milder injury to extensive microvascu...