نتایج جستجو برای: vascular smooth muscle cells
تعداد نتایج: 1847951 فیلتر نتایج به سال:
Vascular progenitor cells are desirable in a variety of therapeutic strategies; however, the lineage commitment of endothelial and smooth muscle cell from a common progenitor is not well-understood. Here, we report the generation of the first dual reporter mouse embryonic stem cell (mESC) lines designed to facilitate the study of vascular endothelial and smooth muscle development in vitro. Thes...
Background and Aims: During vascular calcification (VC), a cardiovascular complication of atherosclerosis, smooth muscle cells (VSMCs) undergo an osteogenic switch secrete heterogeneous population extracellular vesicles (EVs) involved in inflammation oxidative stress. The objective our study is to determine the role mechanism action EVs propagation stress during VC.
Activation of the nuclear receptor/transcription factor, peroxisome proliferator-activated receptor gamma (PPARgamma), is a newly defined target for limiting vascular pathologies. PPARgamma is expressed in human and animal models of vascular disease, with particularly high levels being present in the cells of the neointimal microenvironment. In the present study, we show that intimal smooth mus...
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